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Optic Neuritis (cont.)

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How is optic neuritis diagnosed?

Optic neuritis is suspected in patients with characteristic eye pain and vision loss. A complete medical examination, including chemical analysis of the blood can help rule out related diseases. Tests may include visual acuity testing, pupillary testing, visual field testing, color vision testing, and visualization of the optic disc by direct and indirect ophthalmoscopy.

A person with a first episode of optic neuritis usually undergoes an MRI of the brain to look for central nervous system lesions. MRI with gadolinium enhancement may show an enlarged, enhancing optic nerve. MRI may also help diagnose multiple sclerosis by demonstrating typical abnormalities in the brain.

What is the treatment for optic neuritis?

If a definite cause (such as infection or underlying other disease) is determined, appropriate therapy for that cause can be instituted.

In optic neuritis of undetermined cause or related to multiple sclerosis, vision often returns to normal within two to 12 weeks with no treatment but may also advance to a permanent state of partial or complete visual loss.

Treatment with steroid medications (cortisone medications such as prednisone [Deltasone, Orasone, Prednicen-M, Liquid Pred] and methylprednisolone, [Solu-Medrol]) may speed up vision recovery. Although treatment with steroids have little effect on the final visual outcome in patients with optic neuritis, patients treated initially with intravenous (IV) steroids have about one-half the risk of developing multiple sclerosis in two years as untreated patients do. This effect disappears by the third year of follow up. In addition, patients treated with IV steroids have fewer repeated attacks of optic neuritis than untreated patients.

Ophthalmologists treat patients with optic neuritis with either IV -- followed by oral steroids -- or no treatment at all. For those who are treated, the regimen typically includes three days of IV steroids, followed by about 11 days of oral steroids.

When optic neuritis is associated with MRI lesions suggestive of multiple sclerosis (MS), immunomodulator or immunosuppressive therapy may be prescribed to reduce the incidence of future attacks.


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Source: MedicineNet.com
http://www.medicinenet.com/optic_neuritis/article.htm

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