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Patients receiving OptiMARK™ Injection should be instructed before injection to:
- Inform their physician or health care provider if they are pregnant or breast feeding (see PRECAUTIONS, Pregnancy Category C and Nursing Mothers).
- Inform their physician or health care provider if they have a history of renal and/or liver disease, anemia, hemoglobinopathies, or diseases that affect red blood cells.
- Inform their physician or health care provider if they have a history of asthma or allergic respiratory disorders, seizures, or heart disease.
- Inform their physician or health care provider of all medications they may be taking.
- Inform their physician if they have recently received a GBCA.
GBCAs increase the risk for NSF among patients with impaired elimination of the drugs. To counsel patients at risk for NSF:
- Describe the clinical manifestations of NSF
- Describe procedures to screen for the detection of renal impairment
Instruct the patients to contact their physician if they develop signs or symptoms of NSF following OptiMARK™ administration, such as burning, itching, swelling, scaling, hardening and tightening of the skin; red or dark patches on the skin; stiffness in joints with trouble moving, bending or straightening the arms, hands, legs or feet; pain in the hip bones or ribs; or muscle weakness.
Last reviewed on RxList: 9/9/2013
This monograph has been modified to include the generic and brand name in many instances.
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