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Clinical consequences of overdosage with OptiMARK™ (gadoversetamide injection) Injection have not been reported. Treatment of an overdose is directed toward the support of all vital functions and prompt institution of symptomatic therapy. OptiMARK™ (gadoversetamide injection) Injection has been shown to be dialyzable (see CLINICAL PHARMACOLOGY).

OptiMARK™ (gadoversetamide injection) is contraindicated in patients with:

• chronic, severe kidney disease (glomerular filtration rate, GFR < 30 mL/min/1.73m²), or
• acute kidney injury, or
• known allergic or hypersensitivity reactions to gadolinium, versetamide or any of the inert ingredients.

Last reviewed on RxList: 2/11/2011
This monograph has been modified to include the generic and brand name in many instances.