"In a traditional corneal transplant, the central part of the cornea is removed and a donor cornea is sutured in its place. Image courtesy of Dr. Edward Holland, University of Cincinnati.
Ten years after a transplant, a cornea fro"...
(metipranolol) 0.3% Sterile Ophthalmic Solution
OptiPranolol® (metipranolol ophthalmic solution) 0.3% contains metipranolol, a non-selective beta-adrenergic receptor blocking agent. Metipranolol is a white, odorless, crystalline powder.
The chemical name of metipranolol is (± )-1-(4-Hydroxy-2, 3, 5-trimethylphenoxy)-3-(isopropylamino)-2-propanol-4-acetate.
The chemical structure of metipranolol is:
C17H27NO4 Mol. Wt. 309.40
Each mL of OptiPranolol® contains 3 mg of metipranolol. INACTIVES: Povidone, Glycerin, Hydrochloric Acid, Sodium Chloride, Edetate Disodium, and Purified Water. Sodium Hydroxide and/or Hydrochloric Acid may be added to adjust pH. The product is produced at pH 5.0-5.8 and osmolality 265 to 330 mOsmol/kg. PRESERVATIVE ADDED: Benzalkonium Chloride 0.004%.
What are the possible side effects of metipranolol ophthalmic (OptiPranolol)?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using this medication and call your doctor at once if you have any of these serious side effects:
- severe swelling, itching, burning, redness, pain, or discomfort in or around your eye;
- drainage, crusting, or oozing of your eyes or eyelids;
- vision changes, increased sensitivity of your eyes to light;
- bronchospasm (wheezing, chest tightness, trouble...
What are the precautions when taking metipranolol ophthalmic solution (Optipranolol)?
Before using metipranolol, tell your doctor or pharmacist if you are allergic to it; or to other beta-blockers (e.g., timolol, levobunolol); or if you have any other allergies. This product may contain inactive ingredients (such as preservatives like benzalkonium chloride), which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: severe breathing problems (e.g., asthma or a history of asthma, chronic obstructive pulmonary disease-COPD), certain types of heart rhythm problems (e.g., sinus bradycardia, second- or third-degree atrioventricular block), certain serious heart conditions (e.g.,...
Last reviewed on RxList: 11/13/2008
This monograph has been modified to include the generic and brand name in many instances.
Additional Optipranolol Information
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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