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Brand Names: Optiray 160, Optiray 240, Optiray 300, Optiray 320, Optiray 350

Generic Name: ioversol (Pronunciation: eye oh VERS ol)

• What is ioversol (Optiray Injection)?
• What are the possible side effects of ioversol (Optiray Injection)?
• What is the most important information I should know about ioversol (Optiray Injection)?
• What should I discuss with my health care provider before receiving ioversol (Optiray Injection)?
• How is ioversol used (Optiray Injection)?
• What happens if I miss a dose (Optiray Injection)?
• What happens if I overdose (Optiray Injection)?
• What should I avoid while receiving ioversol (Optiray Injection)?
• What other drugs will affect ioversol (Optiray Injection)?
• Where can I get more information?

What is ioversol (Optiray Injection)?

Ioversol is in a group of drugs called radiopaque (RAY dee oh payk) contrast agents. Ioversol contains iodine, a substance that absorbs x-rays. Radiopaque contrast agents are used to allow blood vessels, organs, and other non-bony tissues to be seen more clearly on a CT scan or other radiologic (x-ray) examination.

Ioversol is used to help diagnose certain disorders of the heart, brain, and blood vessels.

Ioversol may also be used for purposes other than those listed in this medication guide.

What are the possible side effects of ioversol (Optiray Injection)?

Some of the side effects of ioversol can occur up to 24 hours after you have received the medication.

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

• urinating less than usual or not at all;
• severe muscle pain or weakness;
• seizure (convulsions);
• chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general ill feeling;
• sudden numbness or weakness, especially on one side of the body;
• sudden headache, confusion, problems with vision, speech, or balance;
• feeling light-headed, fainting;
• wheezing, trouble breathing;
• fast or slow heartbeat;
• easy bruising, unusual bleeding, or skin changes; or
• swelling of your hands, ankles, or feet.

Other less serious side effects are more likely to occur, such as:

• fever, warmth, or pain;
• skin rash or redness;
• headache; or
• nausea.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about ioversol (Optiray Injection)?

You should not receive ioversol if you have any type of active infection.

Tell your doctor if you have asthma, hay fever, or history of food or drug allergies, especially if you have had any type of reaction to another contrast agent.

Drink extra fluids before and after you receive ioversol. This medication can cause you to get dehydrated, which can lead to dangerous effects on your kidneys. Follow your doctor's instructions about the types and amount of fluids you should drink before and after your test.