(doxycycline) Capsules for Oral Use
ORACEA (doxycycline, USP) Capsules 40 mg are hard gelatin capsule shells filled with two types of doxycycline beads (30 mg immediate release and 10 mg delayed release) that together provide a dose of 40 mg of anhydrous doxycycline (C22H24N2O8). The structural formula of doxycycline, USP is:
with an empirical formula of C22H24N2O8•H2O and a molecular weight of 462.46. The chemical designation for doxycycline is 2-Naphthacenecarboxamide,4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, [4S-(4α, 4aα, 5α, 5aα, 6α,12aα)]-, monohydrate. It is very slightly soluble in water. Inert ingredients in the formulation are: hypromellose, iron oxide red, iron oxide yellow, methacrylic acid copolymer, polyethylene glycol, Polysorbate 80, sugar spheres, talc, titanium dioxide, and triethyl citrate. Active ingredients: Each capsule contains doxycycline, USP in an amount equivalent to 40 mg of anhydrous doxycycline.
What are the possible side effects of doxycycline?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have a serious side effect such as:
- severe headache, dizziness, blurred vision;
- fever, chills, body aches, flu symptoms, swollen glands, rash or itching, joint pain, or general ill feeling;
- urinating less than usual or not at all;
- diarrhea that is watery or bloody
- pale or yellowed skin, dark colored urine, fever, confusion or weakness;
- severe pain in...
What are the precautions when taking doxycycline (Oracea)?
See also Side Effects section.
Before taking doxycycline, tell your doctor or pharmacist if you are allergic to it; or to tetracycline or related drugs (e.g., minocycline); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney disease, liver disease, problems swallowing, esophagus problems (e.g., hiatal hernia, reflux disease-GERD), stomach surgery (e.g., gastrectomy, gastric bypass surgery), lupus.
This medication may make you more sensitive to the sun. Avoid prolonged sun exposure, tanning booths, and sunlamps. Use a sunscreen and wear...
Last reviewed on RxList: 8/12/2013
This monograph has been modified to include the generic and brand name in many instances.
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