(phentolamine mesylate) Injection
Phentolamine mesylate is phenol,3-[[(4,5-dihydro-1H-imidazol-2-yl)methyl](4-methyl-phenyl)amino]-,methanesulfonate (salt ), a non-specific alpha adrenergic blocker. Phentolamine mesylate USP is a white to off-white, odorless crystalline powder with a molecular weight of 377.46.It is sparing soluble in water, soluble in alcohol, and slightly soluble in chloroform. The empirical formulation is C17H19N30•CH403S, and the chemical structure is:
OraVerse (phentolamine mesylate) Injection is a clear, colorless, sterile, non pyrogenic, isotonic, preservative free solution. Each 1.7 mL cartridge contains 0.4 mg phentolamine mesylate, D-mannitol, edetate disodium, and sodium acetate. Either acetic acid or sodium hydroxide is used as necessary to adjust the pH.
Last reviewed on RxList: 6/21/2016
This monograph has been modified to include the generic and brand name in many instances.
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