Small amounts of the candida fungus are present in the mouth, digestive tract, and skin of most healthy people and are normally kept in check by other bacteria and microorganisms in the body. However, certain illnesses, stress, or medications can disturb the delicate balance, causing the fungus candida to grow out of control, causing thrush.
Medications that upset the balance of microorganisms in the mouth and may cause thrush include corticosteroids, antibiotics, and birth control pills. Illnesses or medical situations that make candida infection more likely to develop include uncontrolled diabetes, HIV infection, cancer, dry mouth, or pregnancy (caused by the hormonal changes that occur with pregnancy). People who smoke or wear dentures that don't fit properly also are at increased risk for thrush. In addition, babies can pass the infection to their mothers during breast-feeding.
|
|
ORAVIG
(miconazole) Buccal Tablets
ORAVIG (miconazole) buccal tablets are applied topically to the gum once daily and release miconazole as the buccal tablet gradually dissolves [see CLINICALPHARMACOLOGY].
Miconazole is an imidazole antifungal agent and is described chemically as l-[(2RS)-2-[(2,4-dichlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl]-lH-imidazole with an empirical formula of C18H14Cl4N2O and a molecular weight of 416.13. The structural formula is shown in Figure 1.
Figure 1: Structural Formula of Miconazole
 |
Miconazole drug substance is a white to almost white powder.
ORAVIG contains 50 mg of miconazole base, USP and the following inactive ingredients: hypromellose, USP; milk protein concentrate; corn starch, NF; lactose monohydrate, NF; sodium lauryl sulfate, NF; magnesium stearate, NF; and talc, USP.
Before using miconazole buccal tablets, tell your doctor or pharmacist if you are allergic to miconazole; or if you have any other allergies. This product may contain inactive ingredients (such as milk protein concentrate), which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using this medication, tell your doctor or pharmacist your medical history, especially of: liver problems.
Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).
During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.
It is unknown if this drug passes into breast milk....
Last reviewed on RxList: 6/1/2011
This monograph has been modified to include the generic and brand name in many instances.
Here is a collection of user reviews for the medication Oravig sorted by most helpful.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
Get tips for a healthy mouth.
Copyright © 2012 by WebMD, LLC.
RxList does not provide medical advice, diagnosis or treatment. See additional information.
Updated & New