In this Article

• What is ketoprofen (Orudis)?
• What are the possible side effects of ketoprofen (Orudis)?
• What is the most important information I should know about ketoprofen (Orudis)?
• What should I discuss with my healthcare provider before taking ketoprofen (Orudis)?
• How should I take ketoprofen (Orudis)?
• What happens if I miss a dose (Orudis)?
• What happens if I overdose (Orudis)?
• What should I avoid while taking ketoprofen (Orudis)?
• What other drugs will affect ketoprofen (Orudis)?
• Where can I get more information?

What should I discuss with my healthcare provider before taking ketoprofen (Orudis)?

Taking an NSAID can increase your risk of life-threatening heart or circulation problems, including heart attack or stroke. This risk will increase the longer you use an NSAID. Do not use this medicine just before or after having heart bypass surgery (also called coronary artery bypass graft, or CABG).

NSAIDs can also increase your risk of serious effects on the stomach or intestines, including bleeding or perforation (forming of a hole). These conditions can be fatal and gastrointestinal effects can occur without warning at any time while you are taking an NSAID. Older adults may have an even greater risk of these serious gastrointestinal side effects.

You should not use this medication if you are allergic to ketoprofen, or to aspirin or other NSAIDs.

Before taking ketoprofen, tell your doctor if you are allergic to any drugs, or if you have:

• a history of heart attack, stroke, or blood clot;
• heart disease, congestive heart failure, high blood pressure;
• a history of stomach ulcers or bleeding, bowel problems, diverticulosis;
• liver or kidney disease;
• asthma;
• polyps in your nose; or
• if you smoke.

If you have any of these conditions, you may need a dose adjustment or special tests to safely take this medication.

FDA pregnancy category C. It is not known whether ketoprofen is harmful to an unborn baby. Before taking this medication, tell your doctor if you are pregnant or plan to become pregnant during treatment.

It is not known whether ketoprofen passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Do not give this medicine to a child without the advice of a doctor.

How should I take ketoprofen (Orudis)?

Take this medication exactly as directed on the label, or as it has been prescribed by your doctor. Do not use the medication in larger amounts, or use it for longer than recommended. Ketoprofen should not be used to treat minor aches and pains.

If you take ketoprofen for a long period of time, your doctor may want to check you on a regular basis to make sure this medication is not causing harmful effects. Do not miss any scheduled visits to your doctor.

Store ketoprofen at room temperature, away from moisture, heat, and light.