"Ovary-sparing hysterectomy raises the risk for accelerated menopause, according to a study published online April 4 in Obstetrics Gynecology.
Removing the ovaries at the time of hysterectomy in women at low risk for ovarian ca"...
There is no specific antidote for OSPHENA.
OSPHENA is contraindicated in women with any of the following conditions:
- Undiagnosed abnormal genital bleeding
- Known or suspected estrogen-dependent neoplasia
- Active DVT, pulmonary embolism (PE), or a history of these conditions
- Active arterial thromboembolic disease [for example, stroke and myocardial infarctions (MI)], or a history of these conditions
- Hypersensitivity (for example, angioedema, urticaria, rash, pruritus) to OSPHENA or any ingredients
- OSPHENA is contraindicated in women who are or may become pregnant. OSPHENA may cause fetal harm when administered to a pregnant woman. Ospemifene was embryo-fetal lethal with labor difficulties and increased pup deaths in rats at doses below clinical exposures, and embryo-fetal lethal in rabbits at 10 times the clinical exposure based on mg/m². If this drug is used during pregnancy, or if a woman becomes pregnant while taking this drug, she should be apprised of the potential hazard to a fetus.
Last reviewed on RxList: 3/13/2015
Additional Osphena Information
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