Osteoporosis

In this Article

• What is osteoporosis?
• What are the symptoms of osteoporosis?
• What are the consequences of osteoporosis?
• Why is osteoporosis an important public health issue?
• What factors determine bone strength?
• What are risk factors for developing and causes of osteoporosis?
• How is osteoporosis diagnosed?
• Who should have bone density testing?
• How is osteoporosis treated and prevented?
• Exercise, quitting cigarettes, and curtailing alcohol
• Calcium supplements
• Vitamin D
• Hormone therapy (hormone replacement therapy, menopausal replacement therapy)
• Medications that prevent bone loss and breakdown
• Choosing an osteoporosis medication
• Prevention of osteoporosis caused by long term corticosteroids
• Monitoring osteoporosis therapy medication
• Prevention of hip fractures in elderly persons with osteoporosis
• Osteoporosis At A Glance
• Patient Discussions: Osteoporosis - Symptoms at Onset of Disease

Hormone therapy (menopausal hormone therapy)

Menopausal hormone therapy (previously referred to as hormone replacement therapy or HRT) has been shown to prevent bone loss, increase bone density, and prevent bone fractures. It is useful in preventing osteoporosis in postmenopausal women. Estrogen is available orally (Premarin, Estrace, Estratest, and others) or as a skin patch (Estraderm, Vivelle, and others).

Estrogen is also available in combination with progesterone as pills and patches. Progesterone is routinely given along with estrogen to prevent uterine cancer that might result from estrogen use alone. Women who have had a hysterectomy (surgical removal of the uterus) may take estrogen alone. Nasally delivered estrogen and lower-dose combination pills of estrogen and progesterone are also being studied. However, due to adverse effects of menopausal hormone therapy, such as increased risks of heart attack, stroke, blood clots in the veins, and breast cancer; menopausal hormone therapy is no longer recommended for long-term use in the therapy of osteoporosis. Rather, menopausal hormone therapy is used short-term to relieve menopausal hot flashes.

Every woman needs to have an individualized discussion regarding estrogen replacement with her doctor because each woman will have a different balance of risk and benefit expected from hormone therapy. For more, please read the Hormone Therapy article.

Osteoporosis - Symptoms at Onset of Disease

The MedicineNet physician editors ask:

The symptoms of osteoporosis can vary greatly from patient to patient. What were your symptoms at the onset of your disease?

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