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Overactive Bladder (cont.)

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What are the causes of overactive bladder?

Overactive bladder is typically caused by early, uncontrolled contraction (spasms) of the bladder muscle (detrusor muscle), resulting in an urge to urinate. Overactive bladder is primarily a problem of the nerves and muscles of the bladder that allow for early contraction during the normal relaxation phase of bladder filling. The bladder's contraction in response to filling with urine is one the steps in the normal process of urination. The contraction and relaxation of the detrusor muscle is regulated by the nervous system. Approximately 300 cc of urine in the bladder can signal the nervous to trigger muscles of the bladder to coordinate urination. Voluntary control of the sphincter muscles at the opening of the bladder can hold the urine in the bladder for longer. Up to 600 cc of urine can be contained in a normal adult bladder. For those with OAB, the bladder capacity is typically low (< 200cc).

Overactive bladder typically results from inappropriate contraction of the detrusor muscle regardless of the amount of urine. The most common form of OAB is idiopathic, where the exact cause is not known. However, OAB can result from problems of the nervous system.

The common abnormalities of the nervous system that cause overactive bladder are

Other causes of OAB symptoms include urinary tract infection, bladder stones, urethral strictures, benign prostatic enlargement (BPH), or bladder tumors.

Frequently, no apparent cause of overactive bladder can be determined (idiopathic overactive bladder).

Medically Reviewed by a Doctor on 9/14/2016

Source: MedicineNet.com
http://www.medicinenet.com/overactive_bladder/article.htm

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