Ovide (Malathion) Drug Information: Overdosage and Contraindications

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May 27, 2012

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Head Lice Infestation (Pediculosis) »

What are head lice?

Head lice are parasites that can be found on the heads of people. Infection with head lice is called pediculosis.

(The head louse, Pediculus humanus capitis, is different from the lice that cause body and pubic-hair infections.)

How common is head lice infestation?

Head lice infection is very common. It has been estimated that up to one in every 10 children in school acquires head lice at some time. In one study, the estimated annual cost of head lice infestations in the United States was nearly $1 billion dollars.

Who is at risk for getting head lice?

Anyone who comes in close contact with someone who already has head lice, or even their contaminated clothing and other belongings, is at risk for acquiring head lice. Preschool and elementary school children (3-10 years of age) and their families are infected most often. Girls contract head lice m...

Read the Head Lice Infestation (Pediculosis) article »

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OVERDOSE

Consideratio n should be given, as part of the treatment program, to the high concentration of isopropyl alcohol in the vehicle.

Malathion, although a weaker cholinesterase inhibitor than some other organophosphates, may be expected to exhibit the same symptoms of cholinesterase depletion after accidental ingestion orally. If accidentall y swallowed, vomiting should be induced promptly or the stomach lavaged with 5% sodium bicarbonate solution.

Severe respiratory distress is the major and most serious symptom of organophosphate poisoning re quiring artificial respiration, and atropine may be needed to counteract the symptoms of cholinesterase depletion.

Repeat analyses o f serum and RBC cholinesterase may assist in establishing the diagnosis and formulating a long - ra nge prognosis.

CONTRAINDICATIONS

OVIDE Lotion is contraindicated for neonates and infants because their scalps are more permeable and may have increased absorption of malathion. OVIDE Lotion should also not be used on individuals known to be sensitive to malathion or any of the ingredients in the vehicle.

Last reviewed on RxList: 12/27/2011
This monograph has been modified to include the generic and brand name in many instances.