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Oxandrin Side Effects Center
Medical Editor: Charles Patrick Davis, MD, PhD
Oxandrin (oxandrolone) Tablets is an anabolic steroid and is indicated as adjunctive therapy to promote weight gain after weight loss following extensive surgery, chronic infections, or severe trauma, and in some patients who without definite pathophysiologic reasons fail to gain or to maintain normal weight, to offset the protein catabolism associated with prolonged administration of corticosteroids, and for the relief of the bone pain frequently accompanying osteoporosis. Side effects may include but are not limited to an allergic reaction, swelling of the arms or legs, or voice changes.
Oxandrin is available in 2.5 and 10 mg tablets. The daily adult dosage of Oxandrin is 2.5 mg to 20 mg given in 2 to 4 divided doses. For children the total daily dosage of Oxandrin is less than .1 mg per kilogram body weight or less than .045 mg per pound of body weight; this drug should only be administered by specialists. Serious side effects include liver and spleen complications, tumor formation, and masculinization. Oxandrin may increase sensitivity to oral anticoagulants, and interact with oral hypoglycemic agents, adrenal steroids or ACTH. This drug should not be given during pregnancy. A decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.
Our Oxandrin (oxandrolone) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What is Patient Information in Detail?
Easy-to-read and understand detailed drug information and pill images for the patient or caregiver from Cerner Multum.
Oxandrin in Detail - Patient Information: Side Effects
In rare cases, serious and even fatal cases of liver problems have developed during treatment with oxandrolone. Contact your doctor immediately if you experience abdominal pain, light colored stools, dark colored urine, unusual fatigue, nausea or vomiting, or yellowing of the skin or eyes. These may be early signs of liver problems.
If you experience any of the following serious side effects, contact your doctor immediately or seek emergency medical attention:
- an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);
- swelling of the arms or legs (especially ankles);
- frequent or persistent erections, or breast tenderness or enlargement (male patients); or
- voice changes (hoarseness, deepening), hair loss, facial hair growth, clitoral enlargement, or menstrual irregularities (female patients).
Other less serious side effects may also occur. Talk to your doctor if you experience
- new or worsening acne;
- difficulty sleeping;
- headache; or
- changes in sexual desire.
Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.
Read the entire detailed patient monograph for Oxandrin (Oxandrolone) »
What is Patient Information Overview?
A concise overview of the drug for the patient or caregiver from First DataBank.
Oxandrin Overview - Patient Information: Side Effects
Nausea, vomiting, headache, skin color changes, increased/decreased sexual interest, oily skin, hair loss, and acne may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.
Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
Tell your doctor immediately if any of these unlikely but serious side effects occur: mental/mood changes (such as anxiety, depression, increased anger), trouble sleeping/snoring.
If you are male, tell your doctor immediately if any of these unlikely but serious side effects occur: trouble urinating, breast swelling/tenderness, too frequent/prolonged erections.
Rarely, males may have a painful or prolonged erection lasting 4 or more hours. If this occurs, stop using this drug and seek immediate medical attention, or permanent problems could occur.
This medication can decrease sperm production, an effect that may lower male fertility. Consult your doctor for more details.
If you are female, tell your doctor immediately if any of these unlikely but serious side effects occur: deepening of the voice, hoarseness, unusual facial/body hair growth, enlarged clitoris, irregular menstrual periods.
This medication can cause your body to hold on to extra body water (edema). This can increase your risk of heart failure. Tell your doctor immediately if any of these unlikely but serious signs of water retention or heart failure occur: decreased exercise ability, hands/ankles/feet swelling, unusual tiredness, shortness of breath while lying down.
A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
In the US -
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
Read the entire patient information overview for Oxandrin (Oxandrolone)»
What is Prescribing information?
The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.
Oxandrin FDA Prescribing Information: Side Effects
Patients with moderate to severe COPD or COPD patients who are unresponsive to bronchodilators should be monitored closely for COPD exacerbation and fluid retention.
The following adverse reactions have been associated with use of anabolic steroids:
Hepatic: Cholestatic jaundice with, rarely, hepatic necrosis and death. Hepatocellular neoplasms and peliosis hepatis with long-term therapy (See WARNINGS). Reversible changes in liver function tests also occur including increased bromsulfophthalein (BSP) retention, changes in alkaline phosphatase and increases in serum bilirubin, aspartate aminotransferase (AST, SGOT) and alanine aminotransferase (ALT, SGPT)
Prepubertal: Phallic enlargement and increased frequency or persistence of erections.
Clitoral enlargement, menstrual irregularities.
Hematologic: Bleeding in patients on concomitant oral anticoagulant therapy.
Larynx: Deepening of the voice in females.
Hair:Hirsutism and male pattern baldness in females.
Skin:Acne (especially in females and prepubertal males).
Skeletal: Premature closure of epiphyses in children (See PRECAUTIONS: Pediatric use).
Metabolic/Endocrine: Decreased glucose tolerance (See PRECAUTIONS: Laboratory tests), increased creatinine excretion, increased serum levels of creatinine phosphokinase (CPK). Masculinization of the fetus. Inhibition of gonadotropin secretion.
Drug Abuse And Dependence
Oxandrolone is classified as a controlled substance under the Anabolic Steroids Control Act of 1990 and has been assigned to Schedule III (non-narcotic).
Read the entire FDA prescribing information for Oxandrin (Oxandrolone) »
Additional Oxandrin Information
Oxandrin - User Reviews
Oxandrin User Reviews
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Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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