Oxistat (Oxiconazole) Drug Information: Description, User Reviews, Drug Side Effects, Interactions

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May 26, 2012

Oxistat

Athlete's Foot »

Athlete's foot facts

Athlete's foot is a common dermatitis of the webs of the toes and soles of the feet.
When caused by a fungus, athlete's foot may spread to the palm, groin, and body.
Fungal infections of the feet are contagious and can be spread person to person or by walking on contaminated objects and floors.
Athlete's foot may cause foot itching, burning, pain, and scaling.
When athlete's foot is caused by a fungus, it can be treated with antifungal medications, many of which are available over the counter.
Keeping the feet dry by using cotton socks and breathable shoes can help prevent athlete's foot.

What is athlete's foot?

Athlete's foot is a very common skin condition that affects the sole of the foot and the skin between the toes. It is usually a scaly, red, itchy eruption and occasionally may be weepy and oozing. It affects the feet of ath...

Read the Athlete's Foot article »

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Oxistat User Reviews >>

Oxistat

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OXISTAT®
(oxiconazole nitrate cream) Cream, 1%*

OXISTAT®
(oxiconazole nitrate lotion) Lotion, 1%*

*Potency expressed as oxiconazole

FOR TOPICAL DERMATOLOGIC USE ONLY- NOT FOR OPHTHALMIC OR INTRAVAGINAL USE

DRUG DESCRIPTION

OXISTAT (oxiconazole) Cream and Lotion formulations contain the antifungal active compound oxiconazole nitrate. Both formulations are for topical dermatologic use only.

Chemically, oxiconazole nitrate is 2',4'-dichloro-2-imidazol-1-ylacetophenone (Z)-[0-(2,4-dichlorobenzyl)oxime], mononitrate. The compound has the empirical formula C₁₈H₁₃ON₃Cl₄•HNO₃, a molecular weight of 492.15, and the following structural formula:

OXISTAT® (oxiconazole nitrate cream) Structural Formula Illustration

Oxiconazole nitrate is a nearly white crystalline powder, soluble in methanol; sparingly soluble in ethanol, chloroform, and acetone; and very slightly soluble in water.

OXISTAT Cream contains 10 mg of oxiconazole per gram of cream in a white to off-white, opaque cream base of purified water USP, white petrolatum USP, stearyl alcohol NF, propylene glycol USP, polysorbate 60 NF, cetyl alcohol NF, and benzoic acid USP 0.2% as a preservative.

OXISTAT Lotion contains 10 mg of oxiconazole per gram of lotion in a white to off-white, opaque lotion base of purified water USP, white petrolatum USP, stearyl alcohol NF, propylene glycol USP, polysorbate 60 NF, cetyl alcohol NF, and benzoic acid USP 0.2% as a preservative.

What are the possible side effects of oxiconazole topical (Oxistat)?

Serious side effects of oxiconazole topical use are not expected. Stop using oxiconazole and see your doctor if you experience unusual or severe blistering, itching, redness, peeling, dryness, or irritation of the skin.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at...

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What are the precautions when taking oxiconazole (Oxistat)?

Before using oxiconazole, tell your doctor or pharmacist if you are allergic to it; or to other azole antifungals such as clotrimazole, ketoconazole, or miconazole; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history.

This medication should be used only if clearly needed during pregnancy. Discuss the risks and benefits with your doctor.

This medication passes into breast milk. Consult your doctor before...

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Last reviewed on RxList: 5/5/2008
This monograph has been modified to include the generic and brand name in many instances.