November 26, 2015
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Paget's Disease (cont.)

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What is the prognosis for Paget's disease?

The outlook is generally good, particularly if treatment is given before major changes in the affected bones have occurred. Paget's disease occurs most frequently in the spine, skull, pelvis, thighs, and lower legs. In general, symptoms progress slowly. Paget's disease is not a cancer, and the disease does not spread to normal bones. Treatment can control Paget's disease and lessen symptoms, but treatment does not cure Paget's disease.

Who discovered Paget's disease?

Paget's disease is named after the English surgeon Sir James Paget, who described the condition in 1877. Paget also discovered the worm that causes trichinosis and described what is called Paget's disease of the breast. Together with Rudolph Virchow in Germany, Paget was one of the founders of pathology.

Where can I find more information about Paget's disease?

For further information, contact the Paget's Disease Foundation.

The Paget's Disease Foundation
120 Wall Street, Suite 1602
New York, NY 10005-4001
Phone: 212-509-5335
Fax: 212-509-8492

Medically reviewed by Aimee V. HachigianGould, MD; American Board of Orthopaedic Surgery


Klippel, J.H., et al. Primer on the Rheumatic Diseases. New York: Springer, 2008.

Whyte, Michael P. "Paget's Disease of Bone." New England Journal of Medicine 355 (2006): 593-600.

Medically Reviewed by a Doctor on 11/9/2015


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