Pandel (Hydrocortisone Probutate Cream) Drug Information: Description, User Reviews, Drug Side Effects, Interactions

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May 26, 2012

Pandel

Rash »

What are noninfectious, common rashes localized to a particular anatomical area?

Common, noninfectious rashes are listed below. Since these conditions are not caused by infectious organisms, it is reasonable to attempt to treat them with over-the-counter 1% hydrocortisone cream for a week or so prior to seeking medical attention.

Seborrheic dermatitis: Seborrheic dermatitis is the single most common rash affecting adults. It produces a red, scaling eruption that characteristically affects the scalp, forehead, brows, cheeks, and external ears.

Atopic dermatitis: Atopic dermatitis, often called eczema, is a common disorder of childhood which produces red, itchy, weeping rashes on the inner aspects of the elbows and in back of the knees as well as the cheeks, neck, wrists, and ankles. It is commonly found in patients who also have asthma and hay fever.

Contact dermatitis: Contact dermatitis is a rash that i...

Read the Rash article »

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Pandel

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Pandel®
(hydrocortisone probutate cream) Cream, 0.1%

For Dermatologic Use Only
Not for Ophthalmic Use

DRUG DESCRIPTION

Pandel (hydrocortisone probutate cream) Cream contains hydrocortisone probutate, a synthetic adrenocorticosteroid, for dermatologic use. The topical corticosteroids constitute a class of primarily synthetic steroids used as anti-inflammatory and anti-pruritic agents.

Hydrocortisone probutate is a tasteless and odorless white crystalline powder practically insoluble in hexane or water, slightly soluble in ether, and very soluble in dichloromethane, methanol and acetone. Chemically, it is 11β,17,21-trihydroxypregn-4-ene-3,20-dione 17-butyrate 21-propionate. The structural formula is:

Pandel® (hydrocortisone probutate) Structural Formula Illustration

Molecular Formula: C₂₈H₄₀O₇ Molecular Weight: 488.62

Each gram of Pandel (hydrocortisone probutate cream) Cream, 0.1% contains: 1 mg of hydrocortisone probutate in a cream base of propylene glycol, white petrolatum, light mineral oil, stearyl alcohol, polysorbate 60, sorbitan monostearate, glyceryl monostearate, PEG-20 stearate, glyceryl stearate SE, methylparaben, butylparaben, citric acid, sodium citrate anhy-drous, and purified water.

What are the precautions when taking hydrocortisone probutate cream (Pandel)?

Before using hydrocortisone probutate, tell your doctor or pharmacist if you are allergic to it; or to other corticosteroids (e.g., prednisone, triamcinolone); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history.

Do not use if there is an infection or sore in the area to be treated. Skin infections can become worse when this medication is used. Notify your doctor promptly if redness, swelling, or irritation does not improve.

Rarely, using corticosteroid medications for a long time or over large areas of skin can make it more difficult for your body to respond...

Read All Potential Precautions of Pandel »

Last reviewed on RxList: 6/24/2008
This monograph has been modified to include the generic and brand name in many instances.