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Reversible renal shutdown has been observed in a case where an excessive hematin dose (12.2 mg/kg) was administered in a single infusion. Treatment of this case consisted of ethacrynic acid and mannitol.7
PANHEMATIN is contraindicated in patients with known hypersensitivity to this drug.
7. Dhar, G. J., et al., Transitory Renal Failure Following Rapid Administration of a Relatively Large Amount of Hematin in a Patient with Acute Intermittent Porphyria in Clinical Remission, Acta Med Scand 203:437-443, 1978.This monograph has been modified to include the generic and brand name in many instances.
Last reviewed on RxList: 9/18/2013
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