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Panhematin Side Effects Center
Medical Editor: John P. Cunha, DO, FACOEP
Panhematin (hemin for injection) is an enzyme inhibitor that is made from red blood cells that acts as a mild anticoagulant used to treat the symptoms of occasional attacks of porphyria related to the menstrual cycle in women. Panhematin helps control symptoms such as pain, increased heart rate or blood pressure, and changes in mental status. Common side effects of Panhematin include discoloration of the skin or pain, tenderness, or swelling along your veins.
An intravenous infusion of Panhematin containing a dose of 1 to 4 mg/kg/day of hematin should be given over a period of 10 to 15 minutes for 3 to 14 days based on the clinical signs. Panhematin may interact with blood thinners, birth control pills or hormone replacement therapy, steroids, or barbiturates. Tell your doctor all medications you use. Panhematin should be used only when prescribed during pregnancy. It is unknown if this drug passes into breast milk. Consult your doctor before breastfeeding.
Our Panhematin (hemin for injection) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What is Patient Information in Detail?
Easy-to-read and understand detailed drug information and pill images for the patient or caregiver from Cerner Multum.
Panhematin in Detail - Patient Information: Side Effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using hemin and call your doctor at once if you have a serious side effect such as:
- urinating less than usual or not at all;
- swelling, weight gain, feeling short of breath;
- easy bruising or bleeding; or
- swelling, pain, or irritation around the IV needle.
This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.
Read the entire detailed patient monograph for Panhematin (Hemin)
What is Patient Information Overview?
A concise overview of the drug for the patient or caregiver from First DataBank.
Panhematin Overview - Patient Information: Side Effects
Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
Tell your doctor immediately if any of these highly unlikely but very serious side effects occur: easy bruising or bleeding.
A serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction include: rash, itching/swelling (especially of the face/tongue/throat), dizziness, trouble breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
In the US -
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
Read the entire patient information overview for Panhematin (Hemin)
What is Prescribing information?
The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.
Panhematin FDA Prescribing Information: Side Effects
Clinical Trials Experience
Phlebitis with or without leucocytosis and with or without mild pyrexia has occurred after administration of hematin through small arm veins.
Reversible renal shutdown has occurred with administration of excessive doses (See “PRECAUTIONS” section).
There have been post-marketing literature reports of thrombocytopenia and coagulopathy (including prolonged prothrombin time and prolonged partial thromboplastin time) in patients receiving PANHEMATIN.8 Iron overload and serum ferritin increased have also been reported (See “PRECAUTIONS” section).
To report SUSPECTED ADVERSE REACTIONS, contact Lundbeck at 1-800-455-1141 or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.
Read the entire FDA prescribing information for Panhematin (Hemin)
Additional Panhematin Information
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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