In this Article
- What other names is Papain known by?
- What is Papain?
- How does Papain work?
- Are there safety concerns?
- Are there any interactions with medications?
- Dosing considerations for Papain.
Taking large amounts of papain by mouth is POSSIBLY UNSAFE. In excessive doses, papain can cause severe throat damage. Also, applying raw papain to the skin is POSSIBLY UNSAFE. Skin contact with raw papain can cause irritation and blisters.
There have also been reports of severe allergic reactions.
Special Precautions & Warnings:Pregnancy and breast-feeding: Taking papain by mouth during pregnancy is POSSIBLY UNSAFE. There is a concern that it might cause birth defects or miscarriage. Not enough is known about the safety of using papain during breast-feeding. Do not use it if you are pregnant or breast-feeding.
Allergy to fig or kiwi fruit: One case report suggests that people who are allergic to fig and kiwi might also be allergic to papain.
Bleeding disorders: There is a concern that papain might increase the risk of bleeding in people with a clotting disorder.
Surgery: Papain might increase the risk of bleeding during surgery. Stop taking papain 2 weeks before surgery.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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