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Papaverine Injection Side Effects Center
Medical Editor: John P. Cunha, DO, FACOEP
Papaverine hydrochloride injection is a vasodilator used to treat many conditions that cause spasm of smooth muscle, including heart attack, chest pain, circulation problems, or disorders of the stomach or gallbladder. Papaverine hydrochloride injection is available in generic form. Common side effects of papaverine hydrochloride injection include nausea or stomach discomfort, constipation, diarrhea, skin rash, tired feeling, headache, increased sweating, general discomfort or feeling of being unwell (malaise), loss of appetite, facial flushing (warmth, redness, or tingly feeling), increased heart rate, slight rise in blood pressure, and drowsiness.
Papaverine hydrochloride is administered intravenously (IV) in doses of 1 to 4 mL is repeated every 3 hours as indicated. In the treatment of cardiac extrasystoles, 2 doses may be given 10 minutes apart. Papaverine hydrochloride injection may interact with levodopa (Larodopa, Atamet, Parcopa, Sinemet). Other drugs may interact with papaverine injection. Tell your doctor all prescription and over-the-counter medications and supplements you use. During pregnancy, Papaverine should be used only if prescribed. It may be harmful to a fetus. It is unknown if this drug passes into breast milk or if it could harm a nursing baby. Consult your doctor before breastfeeding.
Our Papaverine hydrochloride injection Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What is Patient Information in Detail?
Easy-to-read and understand detailed drug information and pill images for the patient or caregiver from Cerner Multum.
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Tell your doctor at once if you have a serious side effect such as:
- low fever, nausea, stomach pain, loss of appetite;
- dark urine, clay-colored stools;
- jaundice (yellowing of the skin or eyes);
- warmth, redness, or tingly feeling in your face;
- swelling, pain, or irritation around the IV needle;
- fast heart rate; or
- skin rash, bruising, severe tingling, numbness, pain, muscle weakness.
Less serious side effects may include:
- mild nausea or stomach discomfort;
- constipation, diarrhea;
- mild skin rash;
- tired feeling;
- headache; or
- increased sweating.
This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.
Read the entire detailed patient monograph for Papaverine Injection (Papaverine Hydrochloride Injection)
What is Prescribing information?
The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.
Papaverine Injection FDA Prescribing Information: Side Effects
The following side effects have been reported: general discomfort, nausea, abdominal discomfort, anorexia, constipation or diarrhea, skin rash, malaise, vertigo, headache, intensive flushing of the face, perspiration, increase in the depth of respiration, increase in heart rate, a slight rise in blood pressure, and excessive sedation.
Drug Abuse And Dependence
Drug dependence resulting from the abuse of many of the selective depressants, including papaverine hydrochloride, has been reported.
Read the entire FDA prescribing information for Papaverine Injection (Papaverine Hydrochloride Injection)
Additional Papaverine Injection Information
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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