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Parathyroidectomy (cont.)

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What is a parathyroidectomy?

Parathyroidectomy is the removal of one or more of the parathyroid glands, and it is used to treat hyperparathyroidism.

What is hyperparathyroidism?

Hyperparathyroidism is a condition in which the parathyroid glands produce too much PTH. If there is too much PTH, calcium is removed from the bones and goes into the blood, and there is increased absorption of calcium from the intestine into the blood. This results in increased levels of calcium in the blood and an excess of calcium in the urine. (If there is too little PTH, the blood calcium level can fall to dangerously low levels.) In more serious cases, the bone density will diminish and kidney stones can form. Other non-specific symptoms of hyperparathyroidism include depression, muscle weakness, and fatigue. Every effort is made to medically treat or control these conditions prior to surgery. These efforts include avoiding calcium rich foods, proper hydration (intake of fluids), and medications to avoid osteoporosis.

What causes hyperparathyroidism?

There are two types of hyperparathyroidism, primary and secondary. The most common disorder of the parathyroid glands and one that causes primary hyperparathyroidism, is a small, tumor called a parathyroid adenoma. A parathyroid adenoma is a benign condition in which one parathyroid gland increases in size and produces PTH in excess. (As opposed to parathyroid adenoma, it should be noted that malignant tumors of the parathyroid glands, that is, cancer, is very rare.) In most situations patients are unaware of the adenoma, and they are found when routine blood test results show an elevated blood calcium and PTH level. Less commonly, primary hyperparathyroidism may be caused by overactivity of all of the parathyroid glands, referred to as parathyroid hyperplasia.

With secondary hyperparathyroidism, the secretion of PTH is caused by a nonparathyroid disease, usually kidney failure.


Source: MedicineNet.com
http://www.medicinenet.com/parathyroidectomy/article.htm

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