Patanase Nasal Spray (Olopatadine Hydrochloride Nasal Spray) Drug Information: Description, User Reviews, Drug Side Effects, Interactions

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February 10, 2012

Patanase Nasal Spray

Hay Fever »

What is hay fever? What are the symptoms and signs?

Hay fever is a misnomer. Hay is not a usual cause of this problem, and it does not cause fever. Early descriptions of sneezing, nasal congestion, and eye irritation while harvesting field hay promoted this popular term. Allergic rhinitis is the correct term used to describe this allergic reaction, and many different substances cause the allergic symptoms noted in hay fever. Rhinitis means "irritation of the nose" and is a derivative of rhino, meaning nose. Allergic rhinitis which occurs during a specific season is called "seasonal allergic rhinitis." When it occurs throughout the year, it is called "perennial allergic rhinitis." Rhinosinusitis is the medical term that refers to inflammation of the nasal lining as well as the lining tissues of the sinuses. This term is sometime used because the two conditions frequently occur together.

Symptoms of allergic rhinitis, or hay fever...

Read the Hay Fever article »

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Patanase Nasal Spray User Reviews >>

Patanase Nasal Spray

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PATANASE
(olopatadine hydrochloride) Nasal Spray

DRUG DESCRIPTION

PATANASE (olopatadine hydrochloride) Nasal Spray, 665 micrograms (mcg) is a metered-spray solution for intranasal administration. Olopatadine hydrochloride, the active component of PATANASE (olopatadine hydrochloride nasal spray) Nasal Spray, is a white, water-soluble crystalline powder. The chemical name for olopatadine hydrochloride is (Z)-11-[3-(dimethylamino)propylidene]-6,11-dihydrodibenz[b,e]oxepin-2-acetic acid hydrochloride. It has a molecular weight of 373.88, and its molecular formula is C₂₁H₂₃NO₃ • HCl with the following chemical structure:

PATANASE (olopatadine hydrochloride) Structural Formula Illustration

PATANASE (olopatadine hydrochloride nasal spray) Nasal Spray contains 0.6% w/v olopatadine (base) in a nonsterile aqueous solution with pH of approximately 3.7. After initial priming (5 sprays), each metered spray from the nasal applicator delivers 100 microliters of the aqueous solution containing 665 mcg of olopatadine hydrochloride, which is equivalent to 600 mcg of olopatadine (base) [see DOSAGE AND ADMINISTRATION]. PATANASE (olopatadine hydrochloride nasal spray) Nasal Spray also contains benzalkonium chloride (0.01%), dibasic sodium phosphate, edetate disodium, sodium chloride, hydrochloric acid and/or sodium hydroxide (to adjust pH), and purified water.

What are the possible side effects of olopatadine nasal (Patanase)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using olopatadine and call your doctor at once if you have any of these serious side effects:

nosebleed;
sores inside your nose; or
burning or pain when you urinate.

Less serious side effects may include:

drowsiness;
a bitter taste in your mouth;
headache;
dry mouth,...

Read All Potential Side Effects and See Pictures of Patanase Nasal Spray »

What are the precautions when taking olopatadine hydrochloride nasal spray (Patanase Nasal Spray)?

Before using olopatadine, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history.

This drug may rarely make you drowsy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Limit alcoholic beverages.

During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.

It is not known if this drug passes into breast milk. Consult your doctor before...

Read All Potential Precautions of Patanase Nasal Spray »

Last reviewed on RxList: 4/26/2010
This monograph has been modified to include the generic and brand name in many instances.