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Patanase Nasal Spray

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Patanase Nasal Spray

PATANASE
(olopatadine hydrochloride)

DRUG DESCRIPTION

PATANASE (olopatadine hydrochloride) Nasal Spray, 665 micrograms (mcg) is a metered-spray solution for intranasal administration. Olopatadine hydrochloride, the active component of PATANASE Nasal Spray, is a white, water-soluble crystalline powder. The chemical name for olopatadine hydrochloride is (Z)-11-[3-(dimethylamino)propylidene]-6,11-dihydrodibenz[b,e]oxepin-2-acetic acid hydrochloride. It has a molecular weight of 373.88, and its molecular formula is C21H23NO3 • HCl with the following chemical structure:

PATANASE (olopatadine hydrochloride) Structural Formula Illustration

PATANASE Nasal Spray contains 0.6% w/v olopatadine (base) in a nonsterile aqueous solution with pH of approximately 3.7. After initial priming (5 sprays), each metered spray from the nasal applicator delivers 100 microliters of the aqueous solution containing 665 mcg of olopatadine hydrochloride, which is equivalent to 600 mcg of olopatadine (base) [see DOSAGE AND ADMINISTRATION]. PATANASE Nasal Spray also contains benzalkonium chloride (0.01%), dibasic sodium phosphate, edetate disodium, sodium chloride, hydrochloric acid and/or sodium hydroxide (to adjust pH), and purified water.

What are the possible side effects of olopatadine nasal (Patanase)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using olopatadine nasal and call your doctor at once if you have a serious side effect such as:

  • nosebleed;
  • sores inside your nose;
  • fever; or
  • burning or pain when you urinate.

Less serious side effects may include:

  • drowsiness;
  • a bitter taste in your mouth;
  • headache;
  • dry mouth, sore throat;
  • cough, sneezing, runny nose, cold...

Read All Potential Side Effects and See Pictures of Patanase Nasal Spray »

What are the precautions when taking olopatadine hydrochloride nasal spray (Patanase Nasal Spray)?

Before using olopatadine, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history.

This drug may rarely make you drowsy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Limit alcoholic beverages.

During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.

It is not known if this drug passes into breast milk. Consult your doctor before...

Read All Potential Precautions of Patanase Nasal Spray »

Last reviewed on RxList: 3/5/2012
This monograph has been modified to include the generic and brand name in many instances.

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Patanase Nasal Spray - User Reviews

Patanase Nasal Spray User Reviews

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Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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