Patanase Nasal Spray
Allergy Drugs: Prescription and OTC »
" Allergy medications overview
The arsenal of allergy drugs includes dozens of medications that relieve allergy symptoms when confronted with a trigger known as an allergen. That trigger could be something from a plant, such as polle"...
Patanase Nasal Spray
PATANASE
(olopatadine hydrochloride)
DRUG DESCRIPTION
PATANASE (olopatadine hydrochloride) Nasal Spray, 665
micrograms (mcg) is a metered-spray solution for intranasal administration.
Olopatadine hydrochloride, the active component of PATANASE Nasal Spray, is a
white, water-soluble crystalline powder. The chemical name for olopatadine
hydrochloride is
(Z)-11-[3-(dimethylamino)propylidene]-6,11-dihydrodibenz[b,e]oxepin-2-acetic
acid hydrochloride. It has a molecular weight of 373.88, and its molecular
formula is C21H23NO3 • HCl with the following
chemical structure:
![]() |
PATANASE Nasal Spray contains 0.6% w/v olopatadine (base) in a nonsterile aqueous solution with pH of approximately 3.7. After initial priming (5 sprays), each metered spray from the nasal applicator delivers 100 microliters of the aqueous solution containing 665 mcg of olopatadine hydrochloride, which is equivalent to 600 mcg of olopatadine (base) [see DOSAGE AND ADMINISTRATION]. PATANASE Nasal Spray also contains benzalkonium chloride (0.01%), dibasic sodium phosphate, edetate disodium, sodium chloride, hydrochloric acid and/or sodium hydroxide (to adjust pH), and purified water.
What are the possible side effects of olopatadine nasal (Patanase)?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using olopatadine and call your doctor at once if you have any of these serious side effects:
- nosebleed;
- sores inside your nose; or
- burning or pain when you urinate.
Less serious side effects may include:
- drowsiness;
- a bitter taste in your mouth;
- headache;
- dry mouth, sore throat;
- cough, sneezing, runny nose, cold...
Read All Potential Side Effects and See Pictures of Patanase Nasal Spray »
What are the precautions when taking olopatadine hydrochloride nasal spray (Patanase Nasal Spray)?
Before using olopatadine, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using this medication, tell your doctor or pharmacist your medical history.
This drug may rarely make you drowsy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Limit alcoholic beverages.
During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.
It is not known if this drug passes into breast milk. Consult your doctor before...
Last reviewed on RxList: 3/5/2012
This monograph has been modified to include the generic and brand name in many instances.
Additional Patanase Nasal Spray Information
Patanase Nasal Spray - User Reviews
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
Allergies & Asthma
Improve treatments & prevent attacks.








