"The U.S. Food and Drug Administration today approved Brintellix (vortioxetine) to treat adults with major depressive disorder.
Major depressive disorder (MDD), commonly referred to as depression, is a mental disorder characterized by mo"...
Paxil-CR Patient Information including If I Miss a Dose
In this Article
- What is paroxetine (Paxil-CR)?
- What are the possible side effects of paroxetine (Paxil-CR)?
- What is the most important information I should know about paroxetine (Paxil-CR)?
- What should I discuss with my healthcare provider before taking paroxetine (Paxil-CR)?
- How should I take paroxetine (Paxil-CR)?
- What happens if I miss a dose (Paxil-CR)?
- What happens if I overdose (Paxil-CR)?
- What should I avoid while taking paroxetine (Paxil-CR)?
- What other drugs will affect paroxetine (Paxil-CR)?
- Where can I get more information?
What happens if I miss a dose (Paxil-CR)?
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
What happens if I overdose (Paxil-CR)?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of paroxetine can be fatal.
Overdose symptoms may include extreme drowsiness, vomiting, tremor, confusion, decreased urination, blurred vision, rapid heartbeat, aggression, seizures, and coma.
What should I avoid while taking paroxetine (Paxil-CR)?
Drinking alcohol can increase some of the side effects of paroxetine.
This medication may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.
What other drugs will affect paroxetine (Paxil-CR)?
Cold or allergy medicine, sedatives, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures or anxiety can add to sleepiness caused by paroxetine. Tell your doctor if you regularly use any of these medicines, or any other antidepressant.
Ask your doctor before taking a nonsteroidal anti-inflammatory drug (NSAID) for pain, arthritis, fever, or swelling. This includes aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve, Naprosyn, Naprelan, Treximet), celecoxib (Celebrex), diclofenac (Cataflam, Voltaren), indomethacin (Indocin), meloxicam (Mobic), and others. Taking an NSAID with paroxetine may cause you to bruise or bleed easily.
Many drugs can interact with paroxetine. Below is just a partial list. Tell your doctor if you are using:
- a blood thinner such as warfarin (Coumadin, Jantoven);
- cimetidine (Tagamet);
- fentanyl (Abstral, Actiq, Duragesic, Fentora, Onsolis);
- fosamprenavir (Lexiva);
- linezolid (Zyvox);
- ritonavir (Norvir, Kaletra);
- St. John's wort;
- tamoxifen (Nolvadex, Soltamox);
- theophylline (Elixophyllin, Theo-24, Theochron, Uniphyl);
- tramadol (Ultram, Ultracet);
- tryptophan (also called L-tryptophan);
- heart medication such as digoxin (digitalis, Lanoxin), quinidine (Quin-G), procainamide (Pronestyl), disopyramide (Norpace), flecaininde (Tambocor), mexiletine (Mexitil), propafenone, (Rythmol), and others;
- any other antidepressant such as amitriptyline (Elavil, Vanatrip, Limbitrol), citalopram (Celexa), desipramine (Norpramin), doxepin (Sinequan), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem, Symbyax), imipramine (Tofranil), nortriptyline (Pamelor), sertraline (Zoloft), and others;
- medicine to treat psychiatric disorders, such as chlorpromazine (Thorazine), fluphenazine (Permitil, Prolixin), haloperidol (Haldol), lithium (Lithobid, Eskalith), perphenazine (Trilafon), or risperidone (Risperdal); or
- almotriptan (Axert), frovatriptan (Frova), sumatriptan (Imitrex, Treximet), naratriptan (Amerge), rizatriptan (Maxalt), or zolmitriptan (Zomig).
This list is not complete and other drugs may interact with paroxetine. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.
Where can I get more information?
Your pharmacist can provide more information about paroxetine.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
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Additional Paxil-CR Information
- Paxil-CR Drug Interactions Center: paroxetine hcl oral
- Paxil-CR Side Effects Center
- Paxil-CR Overview including Precautions
- Paxil-CR FDA Approved Prescribing Information including Dosage
Paxil-CR - User Reviews
Paxil-CR User Reviews
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Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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