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This drug should not be used with the following medications because very serious interactions may occur: eletriptan, ergot alkaloids (e.g., ergotamine, dihydroergotamine), drugs which may affect the heart rhythm (QT prolonging drugs such as cisapride, pimozide), ivabradine.

If you are currently using any of these medications listed above, tell your doctor or pharmacist before starting erythromycin.

Many drugs besides erythromycin and those listed above may affect the heart rhythm (QT prolongation), including amiodarone, dofetilide, gatifloxacin, moxifloxacin, procainamide, propafenone, quinidine, sotalol, and thioridazine, among others. Therefore, before using erythromycin, report all medications you are currently using to your doctor or pharmacist.

Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: colchicine, digoxin, live bacterial vaccines, warfarin, drugs affecting liver enzymes that remove erythromycin from your body (such as azole antifungals-including itraconazole and fluconazole, rifamycins-including rifabutin, quinupristin-dalfopristin, calcium channel blockers-including diltiazem and verapamil, certain anti-seizure medicines-including carbamazepine and phenytoin and valproate).

This drug can slow down the removal of other drugs from your body by affecting certain liver enzymes. Some examples of these affected drugs include alfentanil, bromocriptine, buspirone, certain benzodiazepines (alprazolam, midazolam, triazolam), caffeine-containing drugs, cilostazol, corticosteroids (e.g., prednisone), cyclosporine, eplerenone, certain erectile dysfunction medications (sildenafil, vardenafil), eszopiclone, felodipine, certain "statin" drugs (atorvastatin, lovastatin, simvastatin), quetiapine, tacrolimus, theophylline, tolterodine, vinblastine.

Although most antibiotics probably do not affect hormonal birth control such as pills, patch, or ring, some antibiotics may decrease their effectiveness. This could cause pregnancy. Examples include rifamycins such as rifampin or rifabutin. Be sure to ask your doctor or pharmacist if you should use additional reliable birth control methods while using this antibiotic.

This drug can affect the results of certain lab tests. Make sure laboratory personnel and your doctors know you are taking this medication.

This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.

OVERDOSE: If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly.

NOTES: Do not share this medication with others.

This medication has been prescribed for your current condition only. Do not use it later for another infection unless told to do so by your doctor. A different medication may be necessary in those cases.

MISSED DOSE: If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

STORAGE: Store at controlled room temperature below 86 degrees F (30 degrees C) away from light and moisture. Do not store in the bathroom. Keep all medicines away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details about how to safely discard your product.

Information last revised February 2011 Copyright(c) 2011 First DataBank, Inc.