Pediapred (Prednisolone Sodium) Drug Information: Description, User Reviews, Drug Side Effects, Interactions

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February 9, 2012

Pediapred

Wegener's Granulomatosis »

What is Wegener's granulomatosis?

Wegener's granulomatosis is a uncommon type of inflammation of small arteries and veins (vasculitis). It classically involves inflammation of the arteries that supply blood to the tissues of the lungs, the nasal passages (sinuses), and the kidneys. "Incomplete" forms exist that only involve one of these areas. When both lungs and kidneys are affected, the condition is sometimes referred to as generalized Wegener's granulomatosis. When only the lungs are involved, the condition is sometimes referred to as limited Wegener's granulomatosis.

Wegener's granulomatosis usually affects young or middle-aged adults. Although it is uncommon in children, it can affect people at any age. The cause of Wegener's granulomatosis is not known.

What are symptoms of Wegener's granulomatosis?

Symptoms of Wegener's granulomatosis include fatigue, weight loss, fevers, shortness of...

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Prednisolone Sodium
Phosphate, USP, Oral Solution 6.7 mg / 5 mL

DRUG DESCRIPTION

PEDIAPRED (prednisolone sodium phosphate, USP) Oral Solution is a dye free, colorless to light straw colored, raspberry flavored solution. Each 5 mL (teaspoonful) of PEDIAPRED contains 6.7 mg prednisolone sodium phosphate (5 mg prednisolone base) in a palatable, aqueous vehicle.

PEDIAPRED (prednisolone sodium) also contains dibasic sodium phosphate, edetate disodium, methylparaben, purified water, sodium biphosphate, sorbitol, natural and artificial raspberry flavor.

Prednisolone sodium phosphate occurs as white or slightly yellow, friable granules or powder. It is freely soluble in water; soluble in methanol; slightly soluble in alcohol and in chloroform; and very slightly soluble in acetone and in dioxane. The chemical name of prednisolone sodium phosphate is pregna -1,4- diene-3,20-dione, 11,17-dihydroxy -21- (phosphonooxy)-, disodium salt, (11ß)-. The empirical formula is C ₂₁H ₂₇Na ₂O ₈P; the molecular weight is 484.39. Its chemical structure is:

Pharmacological Category: Glucocorticoid

What are the possible side effects of prednisolone?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

problems with your vision;
swelling, rapid weight gain, feeling short of breath;
severe depression, unusual thoughts or behavior, seizure (convulsions);
bloody or tarry stools, coughing up blood;
pancreatitis (severe pain in your upper stomach spreading to your...

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What are the precautions when taking prednisolone sodium (Pediapred)?

Before taking prednisolone, tell your doctor or pharmacist if you are allergic to it; or to prednisone; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: eye disease (such as cataracts, glaucoma), heart problems (such as heart failure, recent heart attack), high blood pressure, liver disease, kidney disease, thyroid problems, diabetes, stomach/intestinal problems (such as diverticulitis, ulcer), brittle bones (osteoporosis), current/past infections (such as tuberculosis, positive tuberculosis test, herpes, fungal), bleeding problems, blood clots, certain...

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Last reviewed on RxList: 1/18/2004
This monograph has been modified to include the generic and brand name in many instances.