Pediotic (Neomycin, Polymyxin B and Hydrocortisone) Patient Information: Side Effects and Drug Images at RxList

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May 27, 2012

Pediotic

Swimmer's Ear »

Swimmer's ear facts

Swimmer's ear, or external otitis, is typically a bacterial infection of the outer ear canal skin and can occur in acute and chronic forms.
Excessive water exposure and frequent instrumentation (usually cotton swabs) of the ear canal are important causative factors.
Itchy ears, a feeling of fullness, swelling, drainage, and pain are early symptoms.
Antibiotic ear drops and avoidance of water are frequently necessary for treatment.
Proper ear care can avoid most infections.

What is "swimmer's ear" or acute external otitis?

External otitis or "swimmer's ear" is an infection of the skin covering the outer ear and ear canal. Acute external otitis is commonly a bacterial infection caused by streptococcus, staphylococcus, or pseudomonas types of bacteria. The swimmer's ear infection is usually caused by excessive water exposure from sw...

Read the Swimmer's Ear article »

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Pediotic

Anatomy of an Ear Infection Slideshow Pictures

Medical Illustration of the Ear Image Collection

Tinnitus (Ringing of the Ears) Slideshow Pictures

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PEDIOTIC (neomycin, polymyxin b and hydrocortisone) ® Suspension Sterile
(neomycin and polymyxin B sulfates and hydrocortisone) Otic Suspension, USP

DRUG DESCRIPTION

PEDIOTIC® Suspension (neomycin and polymyxin B sulfates and hydrocortisone otic suspension) is a sterile antibacterial and anti-inflammatory suspension for otic use. Each mL contains: neomycin sulfate equivalent to 3.5 mg neomycin base, polymyxin B sulfate equivalent to 10,000 polymyxin B units, and hydrocortisone 10 mg (1%). The vehicle contains thimerosal 0.001% (added as a preservative) and the inactive ingredients cetyl alcohol, glyceryl monostearate, mineral oil, polyoxyl 40 stearate, propylene glycol, and Water for Injection. Sulfuric acid may be added to adjust pH. PEDIOTIC (neomycin, polymyxin b and hydrocortisone) ® Suspension has a minimum pH of 4.1, which is less acidic than the minimum pH of 3.0 for CORTISPORIN® Otic Suspension.

Neomycin sulfate is the sulfate salt of neomycin B and C, which are produced by the growth of Streptomyces fradiae Waksman (Fam. Streptomycetaceae). It has a potency equivalent of not less than 600 mcg of neomycin standard per mg, calculated on an anhydrous basis. The structural formulae are:

Neomycin sulfate Structural Formula Illustration

Polymyxin B sulfate is the sulfate salt of polymyxin B1 and B2, which are produced by the growth of Bacillus polymyxa (Prazmowski) Migula (Fam. Bacillaceae). It has a potency of not less than 6,000 polymyxin B units per mg, calculated on an anhydrous basis. The structural formulae are: