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In this Article

• What is peginterferon alfa-2b (Peg-Intron)?
• What are the possible side effects of peginterferon alfa-2b (Peg-Intron)?
• What is the most important information I should know about peginterferon alfa-2b (Peg-Intron)?
• What should I discuss with my healthcare provider before using peginterferon alfa-2b (Peg-Intron)?
• How should I use peginterferon alfa-2b (Peg-Intron)?
• What happens if I miss a dose (Peg-Intron)?
• What happens if I overdose (Peg-Intron)?
• What should I avoid while using peginterferon alfa-2b (Peg-Intron)?
• What other drugs will affect peginterferon alfa-2b (Peg-Intron)?
• Where can I get more information?

What happens if I miss a dose (Peg-Intron)?

Use the medicine as soon as you remember the missed dose, then go back to your regular schedule on the day your next dose is due. If you are more than 2 days late in using your injection, call your doctor for instructions. Do not use extra medicine to make up a missed dose.

What happens if I overdose (Peg-Intron)?

Seek emergency medical attention if you think you have used too much of this medicine. Symptoms of a peginterferon alfa-2b overdose are not known.

What should I avoid while using peginterferon alfa-2b (Peg-Intron)?

Treatment with this medication does not prevent spread of the hepatitis virus to other people. Follow your doctor's instructions about how to prevent passing the disease to another person.

What other drugs will affect peginterferon alfa-2b (Peg-Intron)?

Many drugs can interact with peginterferon alfa-2b. Below is just a partial list. Tell your doctor if you are using:

• a blood thinner such as warfarin (Coumadin);
• fosphenytoin (Cerebyx) or phenytoin (Dilantin);
• methadone (Diskets, Dolophine, Methadose);
• ADHD medication such as Adderall, Ritalin, and others;
• rifampin (Rifadin, Rifater, Rifamate);
• voriconazole (Vfend);
• an antidepressant or anti-psychotic medication;
• cancer medication such as doxorubicin (Adriamycin), lomustine (Ceenu), paclitaxel (Taxol), or tamoxifen (Soltamox);
• cough medicine (prescription or over-the-counter);
• diabetes medications you take by mouth;
• heart or blood pressure medication such as amiodarone (Cordarone, Pacerone), captopril (Capoten), carvedilol (Coreg), flecainide (Tambocor), labetalol (Normodyne, Trandate), metoprolol (Lopressor, Toprol), propranolol (Inderal), and others;
• HIV or AIDS medication;
• medicines used to prevent organ transplant rejection; or
• a sulfa drug (Bactrim, Cotrim, Gantanol, Septra, SMX-TMP, and others).

This list is not complete and there are many other medicines that can interact with peginterferon alfa-2b. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor. Keep a list with you of all the medicines you use and show this list to any doctor or other healthcare provider who treats you.

Where can I get more information?

Your pharmacist can provide more information about peginterferon alfa-2b.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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