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Penetrex® (enoxacin) is a broad-spectrum azafluoroquinolone antibacterial agent for oral administration. Enoxacin is 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-1,8-naphthyridine-3-carboxylic acid sesquihydrate.
Its empirical formula is C 15 H 17 N 4 O 3 F Â· 1 1 / 2 H 2 O, and its molecular weight is 320.32 (anhydrous). Enoxacin is an ivory-to-slightly yellow powder. In dilute aqueous solution, it is unstable in strong sunlight.
Penetrex (enoxacin) is available in 200 mg and 400 mg film-coated tablets. Each "200" and "400" Penetrex tablet contains enoxacin sesquihydrate equivalent to 200 mg and 400 mg of anhydrous enoxacin, respectively. Each Penetrex (enoxacin) 200 mg and 400 mg tablet contains the following inactive ingredients: cellulose microcrystalline NF, colloidal silicon dioxide NF, croscarmellose sodium NF, FD&C Blue No. 2 aluminum lake, hydroxypropyl cellulose NF, hydroxypropyl methylcellulose, magnesium stearate USP, polyethylene glycol, simethicone, sorbic acid, stearate emulsifiers, and titanium dioxide.
Last reviewed on RxList: 12/8/2004
This monograph has been modified to include the generic and brand name in many instances.
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