Penetrex (Enoxacin) Drug Information: Description, User Reviews, Drug Side Effects, Interactions

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May 26, 2012

Penetrex

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Penetrex

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Please Note: This Brand Name drug is no longer available in the US.
(Generic versions may still be available.)

DRUG DESCRIPTION

Penetrex® (enoxacin) is a broad-spectrum azafluoroquinolone antibacterial agent for oral administration. Enoxacin is 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-1,8-naphthyridine-3-carboxylic acid sesquihydrate.

Its empirical formula is C ₁₅H ₁₇N ₄O ₃F Â· 1 ¹/ ₂H ₂O, and its molecular weight is 320.32 (anhydrous). Enoxacin is an ivory-to-slightly yellow powder. In dilute aqueous solution, it is unstable in strong sunlight.

Penetrex (enoxacin) is available in 200 mg and 400 mg film-coated tablets. Each "200" and "400" Penetrex tablet contains enoxacin sesquihydrate equivalent to 200 mg and 400 mg of anhydrous enoxacin, respectively. Each Penetrex (enoxacin) 200 mg and 400 mg tablet contains the following inactive ingredients: cellulose microcrystalline NF, colloidal silicon dioxide NF, croscarmellose sodium NF, FD&C Blue No. 2 aluminum lake, hydroxypropyl cellulose NF, hydroxypropyl methylcellulose, magnesium stearate USP, polyethylene glycol, simethicone, sorbic acid, stearate emulsifiers, and titanium dioxide.

What are the possible side effects of enoxacin (Penetrex)?

If you experience any of the following serious side effects, stop taking enoxacin and seek emergency medical attention or contact your doctor immediately:

an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);
seizures;
confusion or hallucinations;
liver damage (yellowing of the skin or eyes, nausea, abdominal pain or discomfort, unusual bleeding or bruising, severe fatigue); or
muscle or joint pain.

If you...

Read All Potential Side Effects and See Pictures of Penetrex »

Last reviewed on RxList: 12/8/2004
This monograph has been modified to include the generic and brand name in many instances.