"The US Food and Drug Administration (FDA) has approved an expanded indication for onabotulinum toxin A (Botox, Actavis) for the treatment of adults with upper limb spasticity, according to a company news release.
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(Generic versions may still be available.)
Patients should be advised:
- not to take magnesium-, aluminum-, or calcium-containing antacids, bismuth subsalicylate, products containing iron, or multivitamins containing zinc for 8 hours prior to enoxacin or for 2 hours after enoxacin administration (see PRECAUTIONS : Drug Interactions );
- to drink fluids liberally;
- to avoid consumption of caffeine-containing products (certain drugs, coffee, tea, chocolate, certain carbonated beverages) during enoxacin therapy (see PRECAUTIONS : Drug Interactions );
- that convulsions have been reported in patients taking quinolones, including enoxacin, and to notify their physicians before taking this drug if there is a history of this condition;
- to discontinue treatment and inform their physician if they experience pain, inflammation, or rupture of a tendon, and to rest and refrain from exercise until the diagnosis of tendinitis or tendon rupture has been confidently excluded;
- that enoxacin may cause dizziness and lightheadedness and, therefore, patients should know how they react to enoxacin before they operate an automobile or machinery or engage in activities requiring mental alertness and coordination;
- that enoxacin may be associated with hypersensitivity reaction, even following the first dose, and to discontinue the drug at the first sign of a skin rash or other allergic reaction;
- to avoid undue exposure to excessive sunlight while receiving enoxacin and to discontinue therapy if phototoxicity occurs.
Last reviewed on RxList: 12/8/2004
This monograph has been modified to include the generic and brand name in many instances.
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