Penlac (Ciclopirox Topical Solution) Drug Information: Description, User Reviews, Drug Side Effects, Interactions

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May 26, 2012

Penlac

Fungal Nails »

What other conditions can be mistaken for fungal nails?

Here are some other conditions you may have instead of fungal nails:

Lines and ridges: These are common and may be considered normal. They may worsen during pregnancy. A large groove down the center of the nail can be caused by nail biting.
Senile nails: As you age, the nails become brittle, develop ridges and separation of the nail layers at the end of the nail. Try to avoid cleaning solutions, and don't soak the nails in water to avoid worsening of the problem.
Whitish or yellowish nails due to onycholysis. This means separation of the nail from the nail bed. The color you see is air beneath the nail. The treatment is to trim the nail short, don't clean under it, polish if you want to hide the color, and wait two to three months.
Red or black nails due to a hematoma, or blood under the nail, usually occur from trauma ...

Read the Fungal Nails article »

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Penlac User Reviews >>

Penlac

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Quiz: Can You Identify These Skin Conditions?

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Penlac® Nail Lacquer
(ciclopirox) Topical Solution, 8%

For use on fingernails and toenails and immediately adjacent skin only.
Not for use in eyes

DRUG DESCRIPTION

PENLAC® NAIL LACQUER (ciclopirox) Topical Solution, 8%, contains a synthetic antifungal agent, ciclopirox. It is intended for topical use on fingernails and toenails and immediately adjacent skin.

Each gram of PENLAC® NAIL LACQUER (ciclopirox) Topical Solution, 8%, contains 80 mg ciclopirox in a solution base consisting of ethyl acetate, NF; isopropyl alcohol, USP; and butyl monoester of poly[methylvinyl ether/maleic acid] in isopropyl alcohol. Ethyl acetate and isopropyl alcohol are solvents that vaporize after application.

PENLAC ®NAIL LACQUER (ciclopirox) Topical Solution, 8%, is a clear, colorless to slightly yellowish solution.

The chemical name for ciclopirox is 6-cyclohexyl-1-hydroxy-4-methyl-2(1H)-pyridone, with the empirical formula C₁₂H₁₇NO₂ and a molecular weight of 207.27. The CAS Registry Number is [29342-05-0]. The chemical structure is:

Penlac® Nail Lacquer (ciclopirox) Structural Formula Illustration

What are the possible side effects of ciclopirox topical (Loprox, Penlac Nail Lacquer)?

Serious side effects of ciclopirox topical use are not expected to occur. Stop using ciclopirox topical and contact your doctor if you experience unusual or severe itching, redness, burning, dryness, or irritation of the skin or discoloration or other changes in the nails.

Mild burning, itching, or redness may occur with use of ciclopirox topical shampoo.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You...

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What are the precautions when taking ciclopirox topical solution (Penlac)?

Before using ciclopirox, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: diabetes, numbness in fingers/toes (such as diabetic neuropathy).

Before having surgery, tell your doctors or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.

It is unknown if this medication passes into breast milk....

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Last reviewed on RxList: 7/29/2008
This monograph has been modified to include the generic and brand name in many instances.