Recommended Topic Related To:


"During the past several months, we at CDC have been working hard to take steps to increase HPV vaccination coverage among 11-12 year olds, including actively communicating with clinicians and parents about the benefits and safety of this cance"...




No information provided


A severe allergic reaction (e.g., anaphylaxis) after a previous dose of Pentacel (tetanus toxoid conjugate) vaccine, any ingredient of this vaccine, or any other tetanus toxoid, diphtheria toxoid, pertussis-containing vaccine, inactivated poliovirus vaccine or H influenzae type b vaccine is a contraindication to administration of Pentacel vaccine. (See DESCRIPTION). Because of uncertainty as to which ingredient of the vaccine may be responsible, none of the ingredients should be administered. Alternatively, such individuals may be referred to an allergist for evaluation if further immunizations are considered.

The following events are contraindications to administration of any pertussis-containing vaccine, (19) including Pentacel (tetanus toxoid conjugate) vaccine.

  • Encephalopathy (e.g., coma, decreased level of consciousness, prolonged seizures) within 7 days of a previous dose of a pertussis containing vaccine that is not attributable to another identifiable cause.
  • Progressive neurologic disorder, including infantile spasms, uncontrolled epilepsy, progressive encephalopathy. Pertussis vaccine should not be administered to individuals with such conditions until the neurologic status is clarified and stabilized.

Last reviewed on RxList: 7/25/2008
This monograph has been modified to include the generic and brand name in many instances.


Report Problems to the Food and Drug Administration


You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

Women's Health

Find out what women really need.

Use Pill Finder Find it Now See Interactions

Pill Identifier on RxList

  • quick, easy,
    pill identification

Find a Local Pharmacy

  • including 24 hour, pharmacies

Interaction Checker

  • Check potential drug interactions
Search the Medical Dictionary for Health Definitions & Medical Abbreviations