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Pepcid Injection Side Effects Center
Medical Editor: John P. Cunha, DO, FACOEP
Pepcid (famotidine) Injection is a H2 histamine blocker used to treat ulcers of the stomach or intestines. It may be used to prevent intestinal ulcers from returning after treatment. This medication is also used to treat certain stomach and throat problems caused by too much acid (e.g., Zollinger-Ellison syndrome, erosive esophagitis) or a backward flow of stomach acid into the esophagus (gastroesophageal reflux disease-GERD). The brand name of this medication is discontinued, but generic versions may be available. Common side effects include headache, constipation, diarrhea, dizziness, and pain/redness at the injection site.
The recommended dosage for Pepcid Injection Premixed in adult patients is 20 mg intravenously q 12 h. Pepcid Injection may interact with atazanavir, azole antifungals, dasatinib, aspirin or nonsteroidal anti-inflammatories (NSAIDs), or other H2 blockers. Tell your doctor all medications and supplements you use. During pregnancy, Pepcid Injection should be used only when prescribed. This drug passes into breast milk. Consult your doctor before breastfeeding.
Our Pepcid (famotidine) Injection Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What is Patient Information Overview?
A concise overview of the drug for the patient or caregiver from First DataBank.
Pepcid Injection Overview - Patient Information: Side Effects
Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
Tell your doctor right away if you have any serious side effects, including: easy bruising/bleeding, fast/slow/irregular heartbeat, signs of infection (e.g., fever, persistent sore throat, cough), mental/mood changes (e.g., restlessness, confusion, depression), hearing/seeing things that are not there (hallucinations), seizure.
A very serious allergic reaction to this drug is unlikely, but get medical help right away if it occurs. Symptoms of a serious allergic reaction may include: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
In the US -
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
Read the entire patient information overview for Pepcid Injection (Famotidine Injection)
What is Prescribing information?
The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.
Pepcid Injection FDA Prescribing Information: Side Effects
The adverse reactions listed below have been reported during domestic and international clinical trials in approximately 2500 patients. In those controlled clinical trials in which PEPCID Tablets were compared to placebo, the incidence of adverse experiences in the group which received PEPCID Tablets, 40 mg at bedtime, was similar to that in the placebo group.
The following adverse reactions have been reported to occur in more than 1% of patients on therapy with PEPCID in controlled clinical trials, and may be causally related to the drug: headache (4.7%), dizziness (1.3%), constipation (1.2%) and diarrhea (1.7%).
The following other adverse reactions have been reported infrequently in clinical trials or since the drug was marketed. The relationship to therapy with PEPCID has been unclear in many cases. Within each category the adverse reactions are listed in order of decreasing severity:
Cardiovascular: arrhythmia, AV block, palpitation
Musculoskeletal: musculoskeletal pain including muscle cramps, arthralgia
Nervous System/Psychiatric: grand mal seizure; psychic disturbances, which were reversible in cases for which follow-up was obtained, including hallucinations, confusion, agitation, depression, anxiety, decreased libido; paresthesia; insomnia; somnolence. Convulsions, in patients with impaired renal function, have been reported very rarely.
Respiratory: bronchospasm, interstitial pneumonia
Special Senses: tinnitus, taste disorder
The adverse reactions reported for PEPCID Tablets may also occur with PEPCID for Oral Suspension, PEPCID Injection (famotidine injection) Premixed or PEPCID Injection (famotidine injection) . In addition, transient irritation at the injection site has been observed with PEPCID Injection (famotidine injection) .
In a clinical study in 35 pediatric patients < 1 year of age with GERD symptoms [e.g., vomiting (spitting up), irritability (fussing)], agitation was observed in 5 patients on famotidine that resolved when the medication was discontinued.
Read the entire FDA prescribing information for Pepcid Injection (Famotidine Injection)
Additional Pepcid Injection Information
- Pepcid Injection Drug Interactions Center: famotidine iv
- Pepcid Injection Side Effects Center
- Pepcid Injection Overview including Precautions
- Pepcid Injection FDA Approved Prescribing Information including Dosage
Pepcid Injection - User Reviews
Pepcid Injection User Reviews
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Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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