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Percodan

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Percodan

PERCODAN®
(oxycodone and aspirin) Tablets, USP

DRUG DESCRIPTION

Each PERCODAN (aspirin and oxycodone hydrochloride) Tablet contains:

Oxycodone Hydrochloride, USP...............4.8355 mg*
Aspirin, USP............................................325 mg

PERCODAN (aspirin and oxycodone hydrochloride) Tablets also contain the following inactive ingredients: D&C Yellow 10, FD&C Yellow 6, microcrystalline cellulose and corn starch.

The oxycodone hydrochloride component is Morphinan-6-one, 4,5-epoxy-14-hydroxy-3-methoxy-17-methyl-, hydrochloride, (5a)-., a white to off-white, hygroscopic crystals or powder, odorless, soluble in water; slightly soluble in alcohol and is represented by the following structural formula:

Oxycodone structural formula illustration

C18H21NO4•HCl.........................MW 351.82

The aspirin component is 2-(acetyloxy)-, Benzoic acid, a white crystal, commonly tabular or needle-like, or white, crystalline powder. Is odorless or has a faint odor. Is stable in dry air; in moist air it gradually hydrolyzes to salicylic and acetic acids. Slightly soluble in water; freely soluble in alcohol; soluble in chloroform and in ether; sparingly soluble in absolute ether and is represented by the following structural formula:

Aspirin structural formula illustration

C9H8O4.....................MW 180.16

What are the possible side effects of aspirin and oxycodone (Endodan, Percodan, Roxiprin)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

  • black, bloody, or tarry stools, coughing up blood or vomit that looks like coffee ground;
  • shallow breathing, slow heartbeat;
  • fast heart rate;
  • feeling light-headed, fainting;
  • confusion, hallucinations;
  • easy bruising or bleeding; or
  • problems with...

Read All Potential Side Effects and See Pictures of Percodan »

What are the precautions when taking aspirin and oxycodone hydrochloride (Percodan)?

Before taking oxycodone with aspirin, tell your doctor or pharmacist if you are allergic to it; or to other narcotics (such as codeine, hydrocodone), salicylates (such as salsalate), or nonsteroidal anti-inflammatory drugs (such as ibuprofen, naproxen, celecoxib); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: intestinal/bowel disorders (such as paralytic ileus, infectious diarrhea, colitis, blockage), kidney disease, liver disease, bleeding/blood-clotting disorders (such as hemophilia, vitamin K deficiency, low platelet count), stomach problems (such as...

Read All Potential Precautions of Percodan »

*4.8355 mg oxycodone HC1 is equivalent to 4.3346 mg of Oxycodone as the free base.

What are the possible side effects of aspirin and oxycodone (Endodan, Percodan, Roxiprin)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

  • black, bloody, or tarry stools, coughing up blood or vomit that looks like coffee ground;
  • shallow breathing, slow heartbeat;
  • fast heart rate;
  • feeling light-headed, fainting;
  • confusion, hallucinations;
  • easy bruising or bleeding; or
  • problems with...

Read All Potential Side Effects and See Pictures of Percodan »

What are the precautions when taking aspirin and oxycodone hydrochloride (Percodan)?

Before taking oxycodone with aspirin, tell your doctor or pharmacist if you are allergic to it; or to other narcotics (such as codeine, hydrocodone), salicylates (such as salsalate), or nonsteroidal anti-inflammatory drugs (such as ibuprofen, naproxen, celecoxib); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: intestinal/bowel disorders (such as paralytic ileus, infectious diarrhea, colitis, blockage), kidney disease, liver disease, bleeding/blood-clotting disorders (such as hemophilia, vitamin K deficiency, low platelet count), stomach problems (such as...

Read All Potential Precautions of Percodan »

Last reviewed on RxList: 8/12/2010
This monograph has been modified to include the generic and brand name in many instances.

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Percodan - User Reviews

Percodan User Reviews

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You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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