August 31, 2015
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Periochip

"Introduction to dental medications

There are several types of medications that are used to manage a variety of diseases involving the oral cavity (mouth) that are part of good dental care. The medications discussed in this article h"...

Periochip

PerioChip® 2.5mg
(chlorhexidine gluconate)




DRUG DESCRIPTION

PerioChip® (chlorhexidine gluconate) is a small, orange-brown, rectangular chip (rounded at one end) for insertion into periodontal pockets. Each PerioChip weighs approximately 6.9 mg and contains 2.5 mg of chlorhexidine gluconate in a biodegradable matrix of hydrolyzed gelatin (cross-linked with glutaraldehyde). PerioChip also contains glycerin and purified water.

Chlorhexidine gluconate is an antimicrobial agent. Chemically, it is designated as 1,1'-hexamethylenebis [5-(p-chlorophenyl)biguanide] di-D-gluconate, and its molecular formula is C22H30Cl2N10.2C6H12O7. The molecular weight is 897.8. The structural formula of chlorhexidine gluconate is:

PerioChip® (Chlorhexidine gluconate) Structural Formula Illustration

What are the possible side effects of chlorhexidine topical?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using chlorhexidine topical and call your doctor at once if you have a serious side effect such as:

  • severe burning, itching, or redness;
  • blistering or peeling;
  • swelling or severe skin rash; or
  • any other severe irritation of treated skin.

Less serious side effects may occur, and you may have none at all.

This is not a complete list of side effects and others may...

Read All Potential Side Effects and See Pictures of Periochip »

Last reviewed on RxList: 2/3/2012
This monograph has been modified to include the generic and brand name in many instances.

Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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