Periostat

PERIOSTAT®
(doxycycline hyclate) 20 mg Tablets

DRUG DESCRIPTION

Periostat® (doxycycline hyclate) is available as a 20 mg tablet formulation of doxycycline for oral administration.

The structural formula of doxycycline hyclate is:

PERIOSTAT® (doxycycline hyclate) Structural Formula Illustration

with an empirical formula of (C22H24N2O8•HCl)2•C2H6O•H2O and a molecular weight of 1025.89. The chemical designation for doxycycline is 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12 apentahydroxy - 6 - methyl - 1 , 1 1 - dioxo - 2 -naphthacenecarboxamide monohydrochloride, compound with ethyl alcohol (2:1), monohydrate.

Doxycycline hyclate is a yellow to light-yellow crystalline powder which is soluble in water.

Inert ingredients in the formulation are: hydroxypropyl methylcellulose, lactose, magnesium stearate, microcrystalline cellulose, titanium dioxide, and triacetin. Each tablet contains 23 mg of doxycycline hyclate equivalent to 20 mg of doxycycline.

What are the possible side effects of doxycycline?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have a serious side effect such as:

  • severe headache, dizziness, blurred vision;
  • fever, chills, body aches, flu symptoms, swollen glands, rash or itching, joint pain, or general ill feeling;
  • urinating less than usual or not at all;
  • diarrhea that is watery or bloody
  • pale or yellowed skin, dark colored urine, fever, confusion or weakness;
  • severe pain in...

Read All Potential Side Effects and See Pictures of Periostat »

What are the precautions when taking doxycycline hyclate (Periostat)?

See also Side Effects section.

Before taking doxycycline, tell your doctor or pharmacist if you are allergic to it; or to other tetracyclines (such as minocycline); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: trouble swallowing, esophagus problems (such as hiatal hernia or reflux/heartburn).

Before having surgery, tell your doctor or dentist that you are taking this medication.

This medication may make you more sensitive to the sun. Avoid prolonged sun exposure, tanning booths, and sunlamps. Use a sunscreen and wear protective...

Read All Potential Precautions of Periostat »

Last reviewed on RxList: 10/29/2008
This monograph has been modified to include the generic and brand name in many instances.

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Periostat - User Reviews

Periostat User Reviews

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Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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