font size

Peripheral Blood Stem Cell Transplant (cont.)

How are the stem cells removed from the blood?

The blood is filtered through a machine and the stem cells are skimmed off. The removal of the cells is termed pheresis or apheresis (from the Greek "aphairesis" for removal). The stem cells then may be used right away for bone marrow transplant or stored suspended in DMSO and frozen in liquid nitrogen until needed.

How is the patient "prepared" for the transplantation?

Before the transplant is done, the patient receives high-dose chemotherapy and/or radiation therapy over several days to destroy diseased cells (the leukemic cells, lymphoma cells, solid tumor cells, the diseased immune system cells in scleroderma, etc.)

How is the transplantation actually done?

Once the chemotherapy is gone, the stem cells are defrosted and returned to the patient as a blood transfusion. They migrate to the bone marrow, where they can produce new blood and immune cells and replace the cells destroyed by the treatment.

The stem-cell preparation is infused into a vein and, once there in the blood stream, the stem cells act like homing pigeons and head straight for the bone marrow space.

Medically reviewed by Jay B. Zatzkin, MD; American Board of Internal Medicine with subspecialty in Medical Oncology

REFERENCE:

"Bone Marrow Transplantation and Peripheral Blood Stem Cell Transplantation"

cancer.gov


Medically Reviewed by a Doctor on 2/28/2014

Source: MedicineNet.com
http://www.medicinenet.com/peripheral_blood_stem_cell_transplant/article.htm

Cancer

Get the latest treatment options.

advertisement
advertisement
Use Pill Finder Find it Now See Interactions

Pill Identifier on RxList

  • quick, easy,
    pill identification

Find a Local Pharmacy

  • including 24 hour, pharmacies

Interaction Checker

  • Check potential drug interactions
Search the Medical Dictionary for Health Definitions & Medical Abbreviations

NIH talks about Ebola on WebMD