Permax (Pergolide Mesylate) Drug Center: Guide to Drug Information for Professionals, Patients and Caregivers at RxList

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May 27, 2012

Permax

Parkinson's Disease »

What is Parkinson's disease?

Parkinson's disease is the second most common neurodegenerative disorder and the most common movement disorder. It is characterized by progressive loss of muscle control, which leads to trembling of the limbs and head while at rest, stiffness, slowness, and impaired balance. As symptoms worsen, it may become difficult to walk, talk, and complete simple tasks.

The progression of Parkinson's disease and the degree of impairment vary from individual to individual. Many people with Parkinson's disease live long productive lives, whereas others become disabled much more quickly. Premature death is usually due to complications such as falling-related injuries or pneumonia.

In the United States, about 1 million people are affected by Parkinson's disease and worldwide about 5 million. Most individuals who develop Parkinson's disease are 60 years of age or older. Parkinson's disease occurs in approximately 1% of i...

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Please Note: This Brand Name drug is no longer available in the US.
(Generic versions may still be available.)

Permax Drug Center

What is Prescribing information?

The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.

Permax Prescribing Information: Indications & Dosage

Permax (pergolide mesylate) is indicated as adjunctive treatment to levodopa/carbidopa in the management of the signs and symptoms of Parkinson†s disease.

Evidence to support the efficacy of pergolide mesylate as an antiparkinsonian adjunct was obtained in a multicenter study enrolling 376 patients with mild to moderate Parkinson†s disease who were intolerant to l-dopa/carbidopa as manifested by moderate to severe dyskinesia and/or on-off phenomena. On average, the patients evaluated had been on l-dopa/carbidopa for 3.9 years (range, 2 days to 16.8 years). The adminis...

Read the complete drug monograph for Permax »

What is Permax Prescribing Information?

Drug Description - Indications & Dosage - Side Effects & Drug Interactions - Warnings & Precautions - Contraindications - Medication Guide and More

What is Patient information?

Easy-to-read and understand detailed drug information and pill images for the patient or caregiver from Cerner Multum.

Permax Patient Information: Side Effects

Stop taking pergolide and seek emergency medical attention or contact your doctor immediately if you experience any of the following serious side effects:

an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);
irregular heartbeats;
hallucinations (seeing or hearing things that are not real), confusion, or altered consciousness; or
dizziness (especially when rising from a sitting or lying position).

Other, less serious side effects may be more likely to occur. Co...

Read the complete patient information for Permax »

What is Permax Patient Information?

Possible Side Effects - Images - What Is - How Should I Take It - What If I Miss a Dose - What Should I Avoid and More

What is Consumer information?

A concise overview of the drug for the patient or caregiver from First DataBank.

Permax Consumer Information: Uses

This medication is used to treat Parkinson's disease. It can improve your ability to move and decrease shakiness (tremor), stiffness, slowed movement, and unsteadiness. It may also decrease the number of episodes of not being able to move ("on-off syndrome").

Pergolide is an ergot medication that works by helping to restore the balance of a certain natural substance (dopamine) in the brain.

This medication has been withdrawn from the U.S. market due to safety problems (see Side Effects-heart valve problems). Do not stop taking this medication suddenly (see How To Use section). Talk to yo...

Read the complete consumer information for Permax »