Brand Names: Adipost, Anorex-SR, Appecon, Bontril PDM, Bontril Slow Release, Melfiat, Obezine, Phendiet, Plegine, Prelu-2, Statobex

Generic Name: phendimetrazine (Pronunciation: fen di MEH tra zeen)

• What is phendimetrazine (Phendimetrazine Tartrate)?
• What are the possible side effects of phendimetrazine?
• What is the most important information I should know about phendimetrazine?
• What should I discuss with my healthcare provider before taking phendimetrazine?
• How should I take phendimetrazine?
• What happens if I miss a dose?
• What happens if I overdose?
• What should I avoid while taking phendimetrazine?
• What other drugs will affect phendimetrazine?
• Where can I get more information?

What is phendimetrazine (Phendimetrazine Tartrate)?

Phendimetrazine is a sympathomimetic amine, which is similar to an amphetamine. It is also known as an "anorectic" or "anorexigenic" drug. Phendimetrazine stimulates the central nervous system (nerves and brain), which increases your heart rate and blood pressure and decreases your appetite.

Phendimetrazine is used as a short-term supplement to diet and exercise in the treatment of obesity.

Phendimetrazine may also be used for purposes other than those listed in this medication guide.

Bontril PDM

round, green/yellow, imprinted with B 35, V

Bontril Slow Release 105 mg-AMA

green/yellow, imprinted with A, 047

Bontril

green/yellow, imprinted with C, 8647

What are the possible side effects of phendimetrazine?

If you experience any of the following serious side effects, stop taking phendimetrazine and seek emergency medical attention:

• an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives);
• an irregular heartbeat or very high blood pressure (severe headache, blurred vision); or
• hallucinations, abnormal behavior, or confusion.

Other, less serious side effects may be more likely to occur. Continue to take phendimetrazine and talk to your doctor if you experience

• restlessness or tremor,
• nervousness or anxiety,
• headache or dizziness,
• insomnia,
• dry mouth or an unpleasant taste in your mouth,
• diarrhea or constipation, or
• impotence or changes in your sex drive.

Phendimetrazine is habit forming. You can become physically and psychologically dependent on this medication, and withdrawal effects may occur if you stop taking it suddenly after several weeks of continuous use. Talk to your doctor about stopping this medication gradually.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about phendimetrazine?

Use caution when driving, operating machinery, or performing other hazardous activities. Phendimetrazine may cause dizziness, blurred vision, or restlessness, and it may hide the symptoms of extreme tiredness. If you experience these effects, avoid hazardous activities.

Phendimetrazine is habit forming. You can become physically and psychologically dependent on this medication, and withdrawal effects may occur if you stop taking it suddenly after several weeks of continuous use. Talk to your doctor about stopping this medication gradually.

Do not crush, chew, or open any "once-daily" phendimetrazine tablets or capsules. Swallow them whole.