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Phenergan-Codeine

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Phenergan-Codeine

Discontinued Warning IconPlease Note: This Brand Name drug is no longer available in the US.
(Generic versions may still be available.)

Phenergan-Codeine

Phenergan-Codeine Side Effects Center

Medical Editor: John P. Cunha, DO, FACOEP

Phenergan-Codeine (codeine and promethazine) is used to treat cold or allergy symptoms such as runny nose, sneezing, and cough. Codeine is a narcotic that acts a pain reliever and a cough suppressant, and promethazine is an antihistamine. The brand name Phenergan-Codeine is no longer available in the U.S. Generic versions may be available. Common side effects include drowsiness, dizziness, headache, lightheadedness, blurred vision, upset stomach, nausea, constipation, increased sweating, or dry mouth.

The adult dose of codeine and promethazine is 1 tsp (5 ml) every 4 to 6 hours, not to exceed 30 ml in 24 hours. Pediatric dose is based on the child's weight. Codeine and promethazine may interact with sedatives or anxiety medicines, antidepressants, narcotics, phenobarbital, amobarbital, secobarbital, MAO inhibitors, atropine, belladonna, clidinium, dicyclomine, glycopyrrolate, hyoscyamine, methscopolamine, and scopolamine. Tell your doctor all medications you use. During pregnancy, this drug should be used only if prescribed. It is not recommended for use during the last 3 months of pregnancy due to increased risk for withdrawal symptoms such as irritability, abnormal/persistent crying, diarrhea, or seizures. Tell your doctor if you notice symptoms in your newborn. This product passes into breast milk and may rarely have undesirable effects on a nursing infant. Tell your doctor if your infant develops increased sleepiness, difficulty feeding, or trouble breathing. Consult your doctor before breast-feeding. The codeine in this medication may be habit-forming. Withdrawal symptoms may occur if you suddenly stop taking this drug.

Our Phenergan-Codeine (codeine and promethazine) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is Patient Information in Detail?

Easy-to-read and understand detailed drug information and pill images for the patient or caregiver from Cerner Multum.

Phenergan-Codeine in Detail - Patient Information: Side Effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have a serious side effect such as:

  • restless muscle movements in your eyes, tongue, jaw, or neck, tremor (uncontrolled shaking);
  • shallow breathing, slow heartbeat;
  • feeling like you might pass out;
  • jaundice (yellowing of the skin or eyes);
  • confusion, agitation, hallucinations, unusual thoughts or behavior;
  • seizure (convulsions);
  • urinating less than usual or not at all; or
  • very stiff (rigid) muscles, high fever, sweating, fast or uneven heartbeats, fainting.

Less serious side effects may include:

  • dizziness, drowsiness, sleepiness;
  • feeling restless, nervous, or anxious;
  • blurred vision, ringing in your ears;
  • constipation, mild nausea or vomiting;
  • warmth, redness, or tingly feeling under your skin;
  • sleep problems (insomnia);
  • increased sweating;
  • dry mouth; or
  • mild skin rash.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Phenergan-Codeine (Codeine Phosphate and Promethazine HCl) »

What is Patient Information Overview?

A concise overview of the drug for the patient or caregiver from First DataBank.

Phenergan-Codeine Overview - Patient Information: Side Effects

SIDE EFFECTS: Drowsiness, dizziness, headache, lightheadedness, blurred vision, upset stomach, nausea, constipation, or dry mouth may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

This medication can dry up and thicken mucus in your lungs, making it more difficult to breathe and clear your lungs. To help prevent this effect, drink plenty of fluids unless otherwise directed by your doctor.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor immediately if any of these unlikely but serious side effects occur: involuntary behaviors/movements (e.g., fixed upward stare, neck twisting, tongue movements), mental/mood changes (e.g., hallucinations, confusion), ringing in the ears, shaking (tremors), trouble urinating, weakness.

Seek immediate medical attention if any of these rare but very serious side effects occur: easy bruising/bleeding, slow heartbeat, persistent nausea/vomiting, severe abdominal pain, yellowing eyes/skin, seizure.

Codeine is changed into a strong narcotic drug (morphine) in your body. In some people, this change happens faster and more completely than usual, which increases the risk of very serious side effects. Get medical help right away if you notice any of the following: slow/shallow breathing, unusual drowsiness/difficulty waking up, confusion.

This medication may rarely cause a very serious condition called neuroleptic malignant syndrome (NMS). Get medical help right away if you have any of the following symptoms: fever, muscle stiffness/pain/tenderness/weakness, severe tiredness, severe confusion, sweating, fast/irregular heartbeat, dark urine, change in the amount of urine.

A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any of the following symptoms of a serious allergic reaction: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other side effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Read the entire patient information overview for Phenergan-Codeine (Codeine Phosphate and Promethazine HCl)»

What is Prescribing information?

The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.

Phenergan-Codeine FDA Prescribing Information: Side Effects
(Adverse Reactions)

SIDE EFFECTS

No information provided.

FOR COMPLETE PRESCRIBING INFORMATION, REFER TO THE INDIVIDUAL DRUG MONOGRAPHS CODEINE PHOSPHATE; PROMETHAZINE HYDROCHLORIDE.

Read the entire FDA prescribing information for Phenergan-Codeine (Codeine Phosphate and Promethazine HCl) »

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Phenergan-Codeine - User Reviews

Phenergan-Codeine User Reviews

Now you can gain knowledge and insight about a drug treatment with Patient Discussions.

Here is a collection of user reviews for the medication Phenergan-Codeine sorted by most helpful. Patient Discussions FAQs

Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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