Phenergan Vc (Promethazine HCl and Phenylephrine HCl Syrup) Drug Information: Description, User Reviews, Drug Side Effects, Interactions

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February 7, 2012

Phenergan Vc

Vertigo »

Vertigo introduction

Balance is defined as a state of equilibrium. It takes significant amount of work for this to occur in the body. The brain uses inputs from many sources to understand where the body is located in relationship to the world and to allow it to function. Sensory information from the eyes, ears, and position receptors in the rest of the body help keep the body upright and allow it to move in a coordinated fashion.

Information comes to cerebellar lobes located in the base of the brain from the vestibular system in the inner ear, vision from the eyes, and proprioception (position) receptors located throughout the body that send signals through the spinal cord. The cerebellum uses that information to maintain posture, coordinate body motions like walking and also coordinate fine motor skills like using a pen to write.

Vertigo, a feeling of spinning movement and sometimes accompanied by nausea and vomiting, occurs when an...

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Phenergan Vc

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Please Note: This Brand Name drug is no longer available in the US.
(Generic versions may still be available.)

Phenergan VC
(promethazine HCl and phenylephrine HCl) Syrup

DRUG DESCRIPTION

Each 5 mL (one teaspoonful), for oral administration contains: Promethazine hydrochloride 6.25 mg; phenylephrine hydrochloride 5 mg, Alcohol 7%.

Inactive Ingredients: Citric acid, FD& C yellow #6, flavor, methyl- paraben, propylene glycol, propyl- paraben, purified water, saccharin sodium, sodium benzoate, sodium citrate, sucrose. Promethazine hydrochloride, a phenothiazine derivative, is chemically designated as (±)-10-[2-(Dimethylamino) propyl] phenothiazine monohydrochloride.

Promethazine hydrochloride occurs as a white to faint yellow, practically odorless, crystalline powder which slowly oxidizes and turns blue on prolonged exposure to air. It is soluble in water and freely soluble in alcohol. It has a molecular weight of 320.89, and a molecular formula of C₁₇H₂₀N₂S•HCl.

Phenylephrine hydrochloride is a sympathomimetic amine salt which is chemically designated as (-)- m- Hydroxy-a-[(methylamino) methyl] benzyl alcohol hydrochloride. It occurs as white or nearly white crystals, having a bitter taste. It is freely soluble in water and alcohol. Phenylephrine hydrochloride is subject to oxidation and must be protected from light and air. It has a molecular weight of 203.67, and a molecular formula of C₉H₁₃NO₂•HCl.

What are the possible side effects of phenylephrine and promethazine (Phenergan VC, Promethazine VC Plain)?

If you experience any of the following serious side effects, stop taking phenylephrine and promethazine and seek emergency medical attention or contact your doctor immediately:

an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives); or
uncontrollable movements of the eyes, lips, tongue, face, arms, or legs.

Other, less serious side effects may be more likely to occur. Continue to take phenylephrine...

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