Phenergan Vc (Promethazine HCl and Phenylephrine HCl Syrup) Drug Information: Description, User Reviews, Drug Side Effects, Interactions

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May 26, 2012

Phenergan Vc

Allergy »

Allergy facts

Allergy involves an exaggerated response of the immune system.
The immune system is the body's organized defense mechanism against foreign invaders, particularly infections.
Allergens are substances that are foreign to the body and can cause an allergic reaction.
IgE is the allergy antibody.
Allergies can develop at any age.
Your risk of developing allergies is related to your parents' allergy history.

Introduction

In this review you will learn how allergy relates to the immune system. You will begin understanding how and why certain people become allergic. The most common allergic diseases are discussed briefly in this article.

What does an allergy mean?

An allergy refers to an exaggerated reaction by our immune system in response to bodily contact with certain foreign substances. It is exaggerated because these f...

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Phenergan Vc

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Please Note: This Brand Name drug is no longer available in the US.
(Generic versions may still be available.)

Phenergan VC
(promethazine HCl and phenylephrine HCl) Syrup

DRUG DESCRIPTION

Each 5 mL (one teaspoonful), for oral administration contains: Promethazine hydrochloride 6.25 mg; phenylephrine hydrochloride 5 mg, Alcohol 7%.

Inactive Ingredients: Citric acid, FD& C yellow #6, flavor, methyl- paraben, propylene glycol, propyl- paraben, purified water, saccharin sodium, sodium benzoate, sodium citrate, sucrose. Promethazine hydrochloride, a phenothiazine derivative, is chemically designated as (±)-10-[2-(Dimethylamino) propyl] phenothiazine monohydrochloride.

Promethazine hydrochloride occurs as a white to faint yellow, practically odorless, crystalline powder which slowly oxidizes and turns blue on prolonged exposure to air. It is soluble in water and freely soluble in alcohol. It has a molecular weight of 320.89, and a molecular formula of C₁₇H₂₀N₂S•HCl.

Phenylephrine hydrochloride is a sympathomimetic amine salt which is chemically designated as (-)- m- Hydroxy-a-[(methylamino) methyl] benzyl alcohol hydrochloride. It occurs as white or nearly white crystals, having a bitter taste. It is freely soluble in water and alcohol. Phenylephrine hydrochloride is subject to oxidation and must be protected from light and air. It has a molecular weight of 203.67, and a molecular formula of C₉H₁₃NO₂•HCl.

What are the possible side effects of phenylephrine and promethazine (Phenergan VC, Promethazine VC Plain)?

If you experience any of the following serious side effects, stop taking phenylephrine and promethazine and seek emergency medical attention or contact your doctor immediately:

an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives); or
uncontrollable movements of the eyes, lips, tongue, face, arms, or legs.

Other, less serious side effects may be more likely to occur. Continue to take phenylephrine...

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