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(Generic versions may still be available.)
Nervous System: Sedation, sleepiness, occasional blurred vision, dryness of mouth, dizziness; rarely: confusion, disorientation, and extrapyramidal symptoms such as oculogyric crisis, torticollis, and tongue protrusion (usually in association with parenteral injection or excessive dosage).
Cardiovascular: Increased or decreased blood pressure.
Gastrointestinal: Nausea and vomiting.
Nervous System: Restlessness, anxiety, nervousness, and dizziness.
Read the Phenergan Vc (promethazine hcl and phenylephrine hcl syrup) Side Effects Center for a complete guide to possible side effects »
The sedative action of promethazine is additive to the sedative effects of other central nervous system depressants, including alcohol, narcotic analgesics, sedatives, hypnotics, tricyclic antidepressants, and tranquilizers; therefore, these agents should be avoided or administered in reduced dosage to patients receiving promethazine.
Drug: Phenylephrine with prior administration of monoamine oxidase inhibitors (MAOI).
Drug: Phenylephrine with tricyclic antidepressants.
Effect: Pressor response increased.
Drug: Phenylephrine with ergot alkaloids.
Effect: Excessive rise in blood pressure.
Drug: Phenylephrine with bronchodilator sympathomimetic agents and with epinephrine or other sympathomimetics.
Effect: Tachycardia or other arrhythmias may occur.
Drug: Phenylephrine with atropine sulfate.
Drug: Phenylephrine with prior administration of propranolol or other b- adrenergic blockers.
Effect: Cardiostimulating effects blocked.
Drug: Phenylephrine with prior administration of phentolamine or other a- adrenergic blockers.
Effect: Pressor response decreased.
Drug: Phenylephrine with diet preparations, such as amphetamines or phenylpropanolamine.
Effect: Synergistic adrenergic response.
Last reviewed on RxList: 12/8/2004
This monograph has been modified to include the generic and brand name in many instances.
Additional Phenergan Vc Information
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