Phentolamine Mesylate for Injection
Elevated BP May Prematurely Age the Brain »
"Nov. 1, 2012 -- Having even mildly elevated blood pressure at midlife prematurely ages the brain, a new study shows.
Researchers say the early changes seen with higher blood pressure may set the stage for problems with thinking, memor"...
Read the Elevated BP May Prematurely Age the Brain article »
Phentolamine Mesylate for Injection
Phentolamine Mesylate (phentolamine mesylate)
for Injection, USP
DRUG DESCRIPTION
Phentolamine Mesylate (phentolamine mesylate) for Injection USP, is an antihypertensive, available in vials for intravenous and intramuscular administration. Each vial contains phentolamine mesylate (phentolamine mesylate) USP, 5 mg and mannitol USP, 25 mg in sterile, lyophilized form.
Phentolamine mesylate is m-[N-(2-Imidazolin-2-ylmethyl)-p-toluidino]phenol monomethanesulfonate (salt), and its structural formula is:
![]() |
Molecular Formula - C17H19N3O•CH4O3S.............................M.W. - 377.47
Phentolamine mesylate (phentolamine mesylate) USP is a white or off-white, odorless crystalline powder. Its solutions are acid to litmus. It is freely soluble in water and in alcohol, and slightly soluble in chloroform. It melts at about 178°C.
Last reviewed on RxList: 10/21/2008
This monograph has been modified to include the generic and brand name in many instances.
Additional Phentolamine Mesylate for Injection Information
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
Hypertension
Get tips on handling your hypertension.







