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pHisoHex is a bacteriostatic cleansing agent. It cleanses the skin thoroughly and has bacteriostatic action against staphylococci and other gram-positive bacteria. Cumulative antibacterial action develops with repeated use. Cleansing with alcohol or soaps containing alcohol removes the antibacterial residue.
Detectable blood levels of hexachlorophene following absorption through intact skin have been found in subjects who regularly scrubbed with hexachlorophene emulsion 3%. (See WARNINGS for additional information.)
pHisoHex has the same slight acidity as normal skin (pH value 5.0 to 6.0).
The oral LD50 of hexachlorophene in male rats is 66 mg/kg bw, in females 56 mg/kg bw, and in weanling rats 120 mg/kg bw.
In suckling rats (10-days old), it is 9 mg/kg bw.
Last reviewed on RxList: 4/15/2016
This monograph has been modified to include the generic and brand name in many instances.
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