July 30, 2016
Recommended Topic Related To:


"Today, the U.S. Food and Drug Administration cleared the use of the XSTAT 30 wound dressing, an expandable, multi-sponge dressing used to control severe, life-threatening bleeding from wounds in areas that a tourniquet cannot be placed (such as t"...



pHisoHex Side Effects Center

Medical Editor: John P. Cunha, DO, FACOEP

Last reviewed on RxList 1/10/2016

pHisoHex (hexachlorophene detergent) is a skin cleanser that kills certain types of bacteria (e.g., staph). pHisoHex is an antibacterial sudsing emulsion used to help prevent passing germs to others. Many people have no side effects from the use of pHisoHex. Common side effectsof pHisoHex include skin reactions such as redness, dryness, scaling, skin sensitivity to light, or skin swelling. Long/hard rubbing or exposure to heat or cold may worsen these side effects.

The recommended dose of pHisoHex is 5 mL dispensed into the palm. Lather with water and apply to area to be cleansed. pHisoHex may interact with skin products containing alcohol. Tell your doctor all medications and supplements you use. During pregnancy, pHisoHex should be used only when prescribed. It is unknown if this drug passes into breast milk and could have undesirable effects on a nursing infant. Breastfeeding is not recommended while using this drug.

Our pHisoHex (hexachlorophene detergent) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is Patient Information Overview?

A concise overview of the drug for the patient or caregiver from First DataBank.

pHisoHex Overview - Patient Information: Side Effects

SIDE EFFECTS: Skin reactions including redness, dryness, and scaling may occur. Long/hard rubbing or exposure to heat or cold may worsen these effects. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

If your doctor has directed you to use this medication, remember that he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor immediately if any of these rare but very serious side effects occur: mental/mood changes (e.g., agitation, extreme sleepiness), skin infection (e.g., warm/red/itchy skin, swelling, pus), stiff muscles, muscle spasms, difficulty moving/walking, seizures.

A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Read the entire patient information overview for pHisoHex (Hexachlorophene)

What is Prescribing information?

The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.

pHisoHex FDA Prescribing Information: Side Effects
(Adverse Reactions)


Adverse reactions to pHisoHex may include dermatitis and photosensitivity. Sensitivity to hexachlo- rophene is rare; however, persons who have developed photoallergy to similar compounds also may become sensitive to hexachlorophene.

In persons with highly sensitive skin the use of pHisoHex may at times produce a reaction characterized by redness and/or mild scaling or dryness, especially when it is combined with such mechanical factors as excessive rubbing or exposure to heat or cold.

Read the entire FDA prescribing information for pHisoHex (Hexachlorophene)

Phisohex - User Reviews

Phisohex User Reviews

Now you can gain knowledge and insight about a drug treatment with Patient Discussions.

Here is a collection of user reviews for the medication Phisohex sorted by most helpful. Patient Discussions FAQs

Report Problems to the Food and Drug Administration


You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

Women's Health

Find out what women really need.

Use Pill Finder Find it Now See Interactions

Pill Identifier on RxList

  • quick, easy,
    pill identification

Find a Local Pharmacy

  • including 24 hour, pharmacies

Interaction Checker

  • Check potential drug interactions
Search the Medical Dictionary for Health Definitions & Medical Abbreviations