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Physostigmine Salicylate (physostigmine salicylate injection) Injection is a derivative of the Calabar bean, and its active moiety, physostigmine, is also known as eserine. Its chemical structure is:

C₁₅H₂₁N₃O₂•C₇H₆O₃ MW = 413.47

It is soluble in water and a 0.5% aqueous solution has a pH of 5.8.

Physostigmine Salicylate (physostigmine salicylate injection) Injection is available in 2 mL ampules, each mL containing 1 mg of Physostigmine Salicylate (physostigmine salicylate injection) in a vehicle composed of sodium metabisulfite 0.1%, benzyl alcohol 2.0% as a preservative in Water for Injection.

Last reviewed on RxList: 11/10/2008
This monograph has been modified to include the generic and brand name in many instances.