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Pitocin

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Pitocin

Pitocin®
(oxytocin) Injection, USP

DRUG DESCRIPTION

Pitocin (oxytocin injection, USP) is a sterile, clear, colorless aqueous solution of synthetic oxytocin, for intravenous infusion or intramuscular injection. Pitocin is a nonapeptide found in pituitary extracts from mammals. It is standardized to contain 10 units of oxytocic hormone/mL and contains 0.5% Chlorobutanol, a chloroform derivative as a preservative, with the pH adjusted with acetic acid. Pitocin may contain up to 16% of total impurities. The hormone is prepared synthetically to avoid possible contamination with vasopressin (ADH) and other small polypeptides with biologic activity. Pitocin has the empirical formula C43H66N12O12S2 (molecular weight 1007.19). The structural formula is as follows:

Pitocin® (Oxytocin) Structural Formula Illustration

What are the possible side effects of oxytocin (Pitocin, Syntocinon)?

Side effects with oxytocin are not common. Serious side effects include:

  • an allergic reaction (shortness of breath; closing of the throat; hives; swelling of the lips, face, or tongue; rash; or fainting);
  • difficulty urinating;
  • chest pain or irregular heart beat;
  • difficulty breathing;
  • confusion;
  • sudden weight gain or excessive swelling;
  • severe headache;
  • rash;
  • excessive vaginal bleeding; or
  • seizures.

Other, less serious side effects may be more likely to occur. Talk to your doctor if you...

Read All Potential Side Effects and See Pictures of Pitocin »

Last reviewed on RxList: 3/22/2013
This monograph has been modified to include the generic and brand name in many instances.

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Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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