Recommended Topic Related To:

Pitocin

"Many pregnant women take prescription medicines for health problems like diabetes, asthma, seizures, heartburn, and morning sickness. Other women take medicines before they realize they are pregnant.

Not all medicines are safe t"...

Pitocin

Pitocin Side Effects Center

Medical Editor: John P. Cunha, DO, FACOEP

Pitocin (oxytocin injection, USP) is used to induce labor, strengthen labor contractions during childbirth, control bleeding after childbirth, or to induce an abortion. Oxytocin is a natural hormone that causes the uterus to contract. Common side effects include redness or irritation at the injection site, loss of appetite, nausea, vomiting, cramping, or stomach pain.

Pitocin is administered under a physician's supervision. The initial dose of Pitocin should be 0.5-1 mU/min (equal to 3-6 mL of the dilute oxytocin solution per hour). At 30-60 minute intervals the dose should be gradually increased in increments of 1-2 mU/min until the desired contraction pattern has been established. Pitocin may interact with drugs used in anesthesia, prochlorperazine injection, or warfarin. Tell your doctor all medications you use. Pitocin should be used during pregnancy only if prescribed. There are no known indications for use of this medication in the first 3 months of pregnancy other than in relation to spontaneous or induced abortion. Consult your doctor before breast-feeding.

Our Pitocin (oxytocin injection, USP) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is Patient Information in Detail?

Easy-to-read and understand detailed drug information and pill images for the patient or caregiver from Cerner Multum.

Pitocin in Detail - Patient Information: Side Effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Tell your caregivers at once if you have a serious side effect such as:

  • fast, slow, or uneven heart rate;
  • excessive bleeding long after childbirth;
  • headache, confusion, slurred speech, hallucinations, severe vomiting, severe weakness, muscle cramps, loss of coordination, feeling unsteady, seizure (convulsions), fainting, shallow breathing or breathing that stops; or
  • dangerously high blood pressure (severe headache, blurred vision, buzzing in your ears, anxiety, confusion, chest pain, shortness of breath, uneven heartbeats, seizure).

Less serious side effects may include:

  • nausea, vomiting;
  • runny nose, sinus pain or irritation;
  • memory problems; or
  • more intense or more frequent contractions (this is an expected effect of oxytocin).

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Pitocin (Oxytocin Injection) »

What is Prescribing information?

The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.

Pitocin FDA Prescribing Information: Side Effects
(Adverse Reactions)

SIDE EFFECTS

The following adverse reactions have been reported in the mother:

Anaphylactic reaction
Postpartum hemorrhage
Cardiac arrhythmia
Fatal afibrinogenemia
Nausea
Vomiting
Premature ventricular contractions
Pelvic hematoma
Subarachnoid hemorrhage
Hypertensive episodes
Rupture of the uterus

Excessive dosage or hypersensitivity to the drug may result in uterine hypertonicity, spasm, tetanic contraction, or rupture of the uterus.

The possibility of increased blood loss and afibrinogenemia should be kept in mind when administering the drug.

Severe water intoxication with convulsions and coma has occurred, associated with a slow oxytocin infusion over a 24-hour period. Maternal death due to oxytocin-induced water intoxication has been reported.

The following adverse reactions have been reported in the fetus or neonate:

Due to induced uterine motility:

Bradycardia
Premature ventricular contractions and other arrhythmias
Permanent CNS or brain damage
Fetal death
Neonatal seizures have been reported
with the use of Pitocin.

Due to use of oxytocin in the mother:

Low Apgar scores at five minutes
Neonatal jaundice
Neonatal retinal hemorrhage


For medical advice about adverse reactions contact your medical professional. To report SUSPECTED ADVERSE REACTIONS, contact JHP at 1-866-923-2547 or MEDWATCH at 1-800-FDA-1088 (1-800-332-1088) or http://www.fda.gov/medwatch/.

Read the entire FDA prescribing information for Pitocin (Oxytocin Injection) »

A A A

Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


Parenting and Pregnancy

Get tips for baby and you.