Pitressin (Vasopressin) Drug Information: Side Effects and Drug Interactions

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May 27, 2012

Pitressin

Peptic Ulcer »

Peptic ulcer facts

Peptic ulcers are sores in the lining of the stomach or duodenum.
Peptic ulcer formation is related to H. pylori bacteria in the stomach and nonsteroidal anti-inflammatory medications (NSAIDs) in 50% of patients. For the remaining 50% there are miscellaneous or unknown causes.
Ulcer pain may not correlate with the presence or severity of ulceration.
The main symptom of peptic ulcer is upper abdominal pain which can be dull, sharp, or burning. (Bloating and burping are not symptoms of peptic ulcer, and vomiting, poor appetite, and nausea are uncommon symptoms of peptic ulcer.)
Diagnosis of ulcer is made with upper GI series or endoscopy.
Treatment of ulcers involves antibiotic combinations along with stomach acid suppression to eradicate H. pylori, eliminating precipitating factors such as NSAIDs and stomach acid suppression...

Read the Peptic Ulcer article »

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Pitressin

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Please Note: This Brand Name drug is no longer available in the US.
(Generic versions may still be available.)

SIDE EFFECTS

Local or systemic allergic reactions may occur in hypersensitive individuals. The following side effects have been reported following the administration of vasopressin.

Body as a Whole: anaphylaxia (cardiac arrest and/or shock) has been observed shortly after injection of vasopressin.

Cardiovascular: cardiac arrest, circumoral pallor, arrhythmias, decreased cardiac output, angina, myocardial ischemia, peripheral vasoconstruction and gangrene.

Gastrointestinal: abdominal cramps, nausea, vomiting, passage of gas.

Nervous System: tremor, vertigo, "pounding" in head.

Respiratory: bronchial constriction.

Skin and Appendages: sweating, urticaris, cutaneous gangrene.

DRUG INTERACTIONS

1) The following drugs may potentiate the antidiuretic effect of vasopressin when used concurrently: carbamazepine; chlorpropamide; clofibrate; urea; fludrocortisone; tricyclic antidepressants.

2) The following drugs may decrease the antidiuretic effect of vasopressin when used concurrently: demeclocyline; norepinephrine; lithium; heparin, alcohol.

3) Ganglionic blocking agents may produce a marked increase in sensitivity to the pressor effects of vasopressin.

Last reviewed on RxList: 12/8/2004
This monograph has been modified to include the generic and brand name in many instances.