home > drugs a-z list > plavix (clopidogrel bisulfate) drug center

Plavix Drug Center

Plavix (clopidogrel bisulfate) is a thienopyridine class of drug that inhibits platelet aggregation and thus inhibits aspects of blood clotting. Plavix is available in the generic form termed clopidogrel bisulfate. This drug is used to treat patients with acute coronary syndrome, myocardial infarction (MI), peripheral vascular disease and some stroke (ischemic type) patients. The most common side effects are: increased bleeding, nose bleeds, headaches, and bruising.

Plavix is supplied as 75 and 300 mg tablets. For acute coronary syndrome with a non-ST elevation MI, the initial recommended dose is 300 mg, followed by a 75 mg dose per day; for ST elevation MIs, the initial and continuing dose is 75 mg per day. The recommended dose is 75 mg per day for patient with a history of MI, stroke, or peripheral vascular disease. Many doctors may choose to add an aspirin per day along with the Plavix dose in both non-ST elevation and ST elevation MIs as well as to stroke and peripheral vascular disease patients. Patients taking omeprazole have reduced Plavix efficacy due to CYP2C19 enzyme inhibition. (Some patients genetically also have this problem). Plavix should be used during pregnancy only if clearly needed. Most clinicians advise lactating females not to use Plavix, but nursing mothers should discuss the use of this drug with their OB-GYN physicians.

Our Plavix Drug Center provides a comprehensive view of available drug information as well as related drugs, user reviews, supplements, and diseases and conditions.